Tag: Modulator

For research use only. We do not sell to patients. Sirtuin modulator 1 CAS No. : 2070015-26-6 Biological Activity：Sirtuin modulator 1 is a modulator of SIRTl, a homolog of SIRT3, with EC1.5 of < 1 μM, extracted from patent WO 2010071853 A1, Compound No.4. Research Area：Cancer Targets：Sirtuin Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage […]

For research use only. We do not sell to patients. RXR antagonist 1 Biological Activity：RXR antagonist 1 (compound 6a) is a retinoid X receptor (RXR) modulator. RXR antagonist 1 shows potent RXR-antagonistic activity, with a pA2 of 8.06. RXR antagonist 1 can be used for type 2 diabetes research. Research Area：Cancer|Metabolic Disease|Neurological Disease Targets：RAR/RXR Related […]

For research use only. We do not sell to patients. ML169 CAS No. : 1222878-02-5 Biological Activity：ML169 (VU0405652) is a potent, selective and brain penetrant positive allosteric modulator (PAM) of M1 mAChR, with an EC50 of 1.38 µM. ML169 is a MLPCN probe and can be used for Alzheimer’s disease. Research Area：Neurological Disease Targets：mAChR Related […]

For research use only. We do not sell to patients. mGlu4 receptor agonist 1 CAS No. : 1678501-16-0 Biological Activity：mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect. Research Area：Neurological Disease Targets：mGluR Related Small […]

For research use only. We do not sell to patients. m7GpppGmpG ammonium Biological Activity：m7GpppGmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86%. Research Area：Others Targets：DNA/RNA Synthesis Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Risdiplam;TH287 hydrochloride;Direct Black 38;7-TFA-ap-7-Deaza-ddA;BCH001;NKP-1339;Fialuridine;2′-O-MOE-5-Me-rC;PTC299;2′-F-Bz-dC Phosphoramidite Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. O-Phospho-L-serine-13C3,15N CAS No. : 2734706-69-3 Biological Activity：O-Phospho-L-serine-13C3,15N (L-Serine O-phosphate-13C3,15N) is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as […]

For research use only. We do not sell to patients. Cimetidine-d3 CAS No. : 1185237-29-9 Biological Activity：Cimetidine-d3 (SKF-92334-d3) is the deuterium labeled Cimetidine. Cimetidine (SKF-92334) is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine is an inverse agonist. Cimetidine has anti-cancer and anti-inflammatory activity[2][5]. Research Area：Cancer|Endocrinology Targets：Histamine […]

For research use only. We do not sell to patients. V-0219 CAS No. : 878453-71-5 Biological Activity：V-0219 (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 can be used for obesity-associated diabetes research. Research Area：Metabolic Disease Targets：GCGR Related Small Molecules:BETP;GLP-1R agonist 4;VU0453379;PF-06291874;Utreglutide;TT-OAD2;Efocipegtrutide;GLP-1 receptor agonist 2;NNC-0640;Cochinchinenin C;{Val1}-Exendin-3/4;GLP-1(28-36)amide TFA;Exendin-4 […]

For research use only. We do not sell to patients. Velsecorat CAS No. : 1196509-60-0 Biological Activity：AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM. Research Area：Inflammation/Immunology|Endocrinology Targets：Glucocorticoid Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Endocrinology […]

For research use only. We do not sell to patients. RG7800 hydrochloride Biological Activity：RG7800 hydrochloride is an orally active SMN2 splicing modulator, with EC1.5xs of 23 nM and 87 nM for SMN2 splicing and SMN protein; RG7800 hydrochloride has the potential to treat spinal muscular atrophy. Research Area：Neurological Disease Targets：DNA/RNA Synthesis Related Screening Libraries:Clinical Compound […]