Tag: Modulator

For research use only. We do not sell to patients. Tonabersat CAS No. : 175013-84-0 Biological Activity：Tonabersat (SB-220453) is a gap-junction modulator. Tonabersat prevents inflammatory damage in the central nervous system[2][3]. Research Area：Inflammation/Immunology|Neurological Disease Targets：Gap Junction Protein Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Clinical Compound Library;Drug Repurposing […]

For research use only. We do not sell to patients. Posenacaftor CAS No. : 2095064-05-2 Biological Activity：Posenacaftor (PTI-801) is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF). Research Area：Inflammation/Immunology Targets：CFTR Related Small Molecules:PG01;CFTR corrector 8;CP-628006;SRI-37240;Urocortin III (mouse) (free […]

For research use only. We do not sell to patients. AMG-1694 CAS No. : 1361217-07-3 Biological Activity：AMG-1694 is a potent glucokinase–glucokinase regulatory protein (GK-GKRP) disruptors and promotes the dissociation of the GK-GKRP complex with an IC50 of 7 nM, indirectly increasing GK enzymatic activity. AMG-1694 potently reverses the inhibitory effect of GKRP on GK activity […]

For research use only. We do not sell to patients. NMDA receptor potentiator-1 CAS No. : 486427-18-3 Biological Activity：NMDA receptor potentiator-1 (Compound 1368) is a subunit selective NMDA receptor potentiator with IC50s of 4 μM and 5 μM against NR2C and NR2D expression, respectively. Research Area：Neurological Disease Targets：iGluR Related Small Molecules:CIQ;Quinolinic acid-d3;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;ZL006;PYD-106;NMDA-IN-2;JAMI1001A;(S)-Willardiine;Fanapanel;(S)-AMPA;L-Glutamic acid-15N,d5;PDZ1 Domain […]

For research use only. We do not sell to patients. AMPA receptor modulator-3 CAS No. : 211311-39-6 Biological Activity：AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM). AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory[2]. Research Area：Neurological Disease Targets：iGluR Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. Clomiphene citrate CAS No. : 50-41-9 Biological Activity：Clomiphene citrate (Clomifene citrate) is a selective estrogen receptor modulator. Target: Estrogen Receptor/ERR Clomifene citrate (CC) acted as an estrogen antagonist regardless of the concentration of E2 added together. In conclusion, CC acts as an estrogen agonist/antagonist via […]

For research use only. We do not sell to patients. IL-17A modulator-2 CAS No. : 2748749-47-3 Biological Activity：IL-17A modulator-2 is a IL-17A modulator, extracted from patent WO2021239743+A1, example 27. IL-17A modulator-2 inhibits the biological action of IL-17A with a pIC50 of 8.3. IL-17A modulator-2 can be used for the research of diseases or disorders associated […]

For research use only. We do not sell to patients. Flutax-2 (5/6-mixture) Biological Activity：Flutax-2 (5/6-mixture) is an active fluorescent derivative of Taxol. Flutax-2 (5/6-mixture) binds to polymerized α,β-tubulin dimers. Flutax-2 (5/6-mixture) is able to stabilize microtubules of intact T. gallinae and T. foetus trophozoites[1]. Research Area：Cancer Targets：Microtubule/Tubulin Related Screening Libraries:Bioactive Compound Library Plus; Related Small […]

For research use only. We do not sell to patients. S1PR1-MO-1 CAS No. : 1149727-61-6 Biological Activity：S1PR-MO-1 is the modulator of sphingosine-1-phosphate receptor, used for research of hyperproliferative, inflammatory diseases. Research Area：Inflammation/Immunology Targets：LPL Receptor Related Small Molecules:GSK2018682;Ozanimod hydrochloride;BMS-986020 sodium;S1p receptor agonist 2;ONO-9780307;Siponimod hemifumarate;S1P2 antagonist 1;S1P1 agonist III;Ceralifimod;Ki16425;H2L 5765834;S1PR1 agonist 2;RP101442;S1PR1 agonist 1;CS-2100;ASP1126;1-Oleoyl lysophosphatidic acid;Ex26;RP-001 hydrochloride;VPC […]

For research use only. We do not sell to patients. PF-06648671 CAS No. : 1587727-31-8 Biological Activity：PF-06648671 is a novel, brain‐penetrable, and orally active γ‐secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease. Research Area：Neurological Disease Targets：γ-secretase Related Screening […]