Tag: Modulator

For research use only. We do not sell to patients. Substance P TFA CAS No. : 148470-19-3 Biological Activity：Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). Research Area：Endocrinology|Neurological Disease|Cancer Targets：Neurokinin Receptor|Endogenous […]

For research use only. We do not sell to patients. JAK2 JH2 binder-1 Biological Activity：JAK2 JH2 binder-1 (compound 11) is a potent and selective JAK2 JH2 binder, with a Kd of 37.1 nM. JAK2 JH2 binder-1 has the potential for various myeloproliferative neoplasms research. Research Area：Cancer Targets：JAK Related Small Molecules:AZ-3;JAK3/BTK-IN-1;AT9283;Benzene hexabromide;(E/Z)-Zotiraciclib;JAK-IN-10;Baricitinib-d3;JAK3-IN-6;Coumermycin A1;Deucravacitinib;Momelotinib-3,3,5,5-d4;SJ10542;Delgocitinib;Upadacitinib;α7 nAchR-JAK2-STAT3 agonist 1;Filgotinib-d4;AZD-1480;JAK-IN-20;JAK3 […]

For research use only. We do not sell to patients. Balcinrenone CAS No. : 1850385-64-6 Biological Activity：Balcinrenone (AZD9977) is a potent, selective, and orally active mineralocorticoid receptor (MR) modulator. Balcinrenone is used for heart failure, and chronic kidney disease research. Research Area：Metabolic Disease|Cardiovascular Disease Targets：Mineralocorticoid Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library […]

For research use only. We do not sell to patients. (R)-Olacaftor CAS No. : 1899111-41-1 Biological Activity：(R)-Olacaftor ((R)-VX-440) is a Cystic fibrosis transmembrane conductance regulator (CFTR) modulator. (R)-Olacaftor has good potential for the study of cystic fibrosis (CF). Research Area：Others Targets：CFTR Related Small Molecules:PG01;CFTR corrector 8;CP-628006;SRI-37240;Urocortin III (mouse) (free acid);NJH-2-056;Elexacaftor;GlyH-101;Cavosonstat;Kobusin;GLPG1837;(R)-Posenacaftor sodium;GLPG2451;CFTR corrector 9;CFTR corrector 2;Vanzacaftor;CFTR […]

For research use only. We do not sell to patients. L-Stepholidine CAS No. : 16562-13-3 Biological Activity：L-Stepholidine (Stepholidine) exhibits mixed dopamine D1 receptor agonist and D2 antagonist properties. L-Stepholidine has neuroprotective effect and inhibits Heroin-induced reinstatement. L-Stepholidine is a potential medication for the research of opiate addiction[2][3]. Research Area：Neurological Disease Targets：Dopamine Receptor Related Small Molecules:Alizapride […]

For research use only. We do not sell to patients. VU0155094 CAS No. : 731006-86-3 Biological Activity：VU0155094 is a positive allosteric modulator with differential activity at the various group III mGluRs. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 hydrochloride;Cinnabarinic acid;LY379268;AZD 9272;mGluR2 antagonist 1;ABP688;FTIDC;MPPG;L-AP3;VU6001966;VU0155041 sodium;VU 0364439;trans-ACPD;AZD-8529 mesylate;VU 0357121;PHCCC;HexylHIBO;VU0650786 Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. DL-Norepinephrine-d6 hydrochloride CAS No. : 1219803-04-9 Biological Activity：DL-Norepinephrine-d6 hydrochloride is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine．DL-Norepinephrine hydrochloride is a neurotransmitter targets α1 and β1 adrenoceptors, has an increasing effect on subendocardial […]

For research use only. We do not sell to patients. Flibanserin hydrochloride CAS No. : 147359-76-0 Biological Activity：Flibanserin (BIMT-17; BIMT-17BS) hydrochloride is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin hydrochloride binds to dopamine D4 receptors with an Ki value of […]

For research use only. We do not sell to patients. D2343 CAS No. : 72734-63-5 Biological Activity：D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor. Research Area：Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine hemitartrate;ADRA1D receptor antagonist 1;Solabegron Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. TQS CAS No. : 353483-92-8 Biological Activity：TQS is a α7 nicotinic acetylcholine receptor (nAChR) positive allosteric modulator. TQS can be used for the research of neuroinflammatory pain. Research Area：Inflammation/Immunology|Neurological Disease Targets：nAChR Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound […]