Tag: Modulator

For research use only. We do not sell to patients. IRAK inhibitor 3 CAS No. : 1012343-93-9 Biological Activity：IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. Research Area：Inflammation/Immunology Targets：IRAK Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library; Related Small Molecules:IRAK4-IN-8;Edecesertib;IRAK4-IN-22;IRAK inhibitor 2;PROTAC IRAK4 degrader-3;IRAK […]

For research use only. We do not sell to patients. Sonlicromanol hydrochloride CAS No. : 2162149-24-6 Biological Activity：Sonlicromanol (KH176) hydrochloride, a chemical entity derivative of Trolox, is a blood-brain barrier permeable ROS-redox modulator. Sonlicromanol (KH176) hydrochloride is used in the study for mitochondrial disorders. Research Area：Metabolic Disease Targets：Reactive Oxygen Species Related Screening Libraries:Drug Repurposing Compound […]

For research use only. We do not sell to patients. PPARα-MO-1 CAS No. : 810677-36-2 Biological Activity：PPARα-MO-1 is a potent PPARα modulator extracted from patent WO/2004/110982A1, formula I. Research Area：Metabolic Disease Targets：PPAR Related Small Molecules:Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Licarin B;Mifobate;PPARγ/GR modulator 1;Daidzein-d4;Ciglitazone;MK-886;CP-775146;FK614;Muraglitazar;Magnolol;PPAR agonist 1;PPARα agonist 1;PPARγ phosphorylation inhibitor 1;GSK0660;Glabridin;CUDA;Norathyriol;Saroglitazar;GW 9578;Elafibranor;ST247;Bilobetin Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. JNJ-61432059 CAS No. : 2035814-50-5 Biological Activity：JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, resulting in robust […]

For research use only. We do not sell to patients. Bocidelpar CAS No. : 2095128-20-2 Biological Activity：Bocidelpar is a modulator of peroxisome proliferator-activated receptor delta (PPAR-δ). Bocidelpar improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy (DMD) muscle cells (extracted from patent WO2017062468A1, compound 2b). Research Area：Metabolic Disease Targets：PPAR Related Screening Libraries:Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. Ercalcidiol CAS No. : 21343-40-8 Biological Activity：Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status. Research Area：Metabolic Disease Targets：VD/VDR|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus; Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy […]

For research use only. We do not sell to patients. CXCR4 modulator-2 CAS No. : 2488943-55-9 Biological Activity：CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model. Research […]

For research use only. We do not sell to patients. NJH-2-057 Biological Activity：NJH-2-057 is an EN523 OTUB1 recruiter linked to lumacaftor, a drug used to treat cystic fibrosis that binds ΔF508-CFTR. Research Area：Others Targets：CFTR Related Small Molecules:PG01;CFTR corrector 8;CP-628006;SRI-37240;Urocortin III (mouse) (free acid);NJH-2-056;Elexacaftor;GlyH-101;Cavosonstat;Kobusin;GLPG1837;(R)-Posenacaftor sodium;GLPG2451;CFTR corrector 9;CFTR corrector 2;Vanzacaftor;CFTR corrector 4;Posenacaftor sodium;KM11060;Nesolicaftor;Galicaftor;Tezacaftor;PPQ-102;SRI-41315;CFTR corrector 6 Trending products：Recombinant […]

For research use only. We do not sell to patients. Rapastinel Trifluoroacetate CAS No. : 1435786-04-1 Biological Activity：Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. Rapastinel Trifluoroacetate has the potential for major depressive disorder treatment. Research Area：Neurological Disease Targets：iGluR Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive […]

For research use only. We do not sell to patients. BRD9500 CAS No. : 1630760-75-6 Biological Activity：BRD9500 is an orally active phosphodiesterases 3 (PDE3) inhibitor with IC50s of 10 and 27 nM for PDE3A and PDE3B, respectively. Antitumor activity. Research Area：Cancer Targets：Phosphodiesterase (PDE) Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Orally Active Compound […]