Tag: Inhibitor|Inducer

For research use only. We do not sell to patients. Tomatidine CAS No. : 77-59-8 Biological Activity：Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. Tomatidine activates autophagy either in mammal cells or C elegans[2]. Research Area：Inflammation/Immunology|Cardiovascular Disease Targets：Autophagy|NF-κB|Endogenous Metabolite|JNK Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation […]

For research use only. We do not sell to patients. Tubulin polymerization-IN-13 CAS No. : 2426665-56-5 Biological Activity：Tubulin polymerization-IN-13 (Compound 4f) is a tubulin polymerization inhibitor (IC50=0.37 μM). Tubulin polymerization-IN-13 shows anti-proliferative activity against cancer cells, induces apoptosis and potential antivascular activity. Research Area：Cancer Targets：Microtubule/Tubulin|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Tirbanibulin dihydrochloride;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor […]

For research use only. We do not sell to patients. Topoisomerase II inhibitor 7 CAS No. : 2697171-03-0 Biological Activity：Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis. Research Area：Cancer Targets：Topoisomerase|Apoptosis Related […]

For research use only. We do not sell to patients. EGFR-IN-51 CAS No. : 2418549-32-1 Biological Activity：EGFR-IN-51 (Compound 6) is a potent EGFR inhibitor with IC50 values of 0.493, 102.60 and 461.63 µM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-51 shows cytotoxic activity against cancer cell lines and induces apoptosis. Research Area：Cancer Targets：EGFR|Apoptosis […]

For research use only. We do not sell to patients. Nitrendipine-d5 CAS No. : 2469554-26-3 Biological Activity：Nitrendipine-d5 (AY-E-5009-d5) is the deuterium labeled Nitrendipine. Nitrendipine (BAY-E-5009), an analogue of Nifedipine (HY-B0284), is a dihydropyridine calcium channel blocker with vasodilator action. Nitrendipine has antihypertensive effect[2][3][4]. Research Area：Cardiovascular Disease Targets：Autophagy|Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM 1003;Glaucine;Efonidipine hydrochloride […]

For research use only. We do not sell to patients. 3-Nitropropanoic acid CAS No. : 504-88-1 Biological Activity：3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM[2]. Research Area：Infection|Metabolic Disease Targets：Bacterial|Apoptosis Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. VEGFR-2-IN-11 Biological Activity：VEGFR-2-IN-11 (Compound 8h) is a potent VEGFR-2 inhibitor with an IC50 of 60.27 nM. VEGFR-2-IN-11 shows antitumor activity and induces cell apoptosis. Research Area：Cancer Targets：VEGFR|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;(Z)-FeCP-oxindole;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;VEGFR-2-IN-24;Ecteinascidin 770;MDM2-p53-IN-15;BMS-690514;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  […]

For research use only. We do not sell to patients. Tubulin inhibitor 23 CAS No. : 170488-57-0 Biological Activity：Tubulin inhibitor 23 is a potent Tubulin inhibitor with an IC50 of 4.8 µM. Tubulin inhibitor 23 induces cell apoptosis. Tubulin inhibitor 23 shows antiangiogenic activity in a dose-dependent manner. Tubulin inhibitor 23 has the potential for […]

For research use only. We do not sell to patients. MK-8745 CAS No. : 885325-71-3 Biological Activity：MK-8745 is an aurora A kinase inhibitor with an IC50 of 0.6 nM. Research Area：Cancer Targets：Aurora Kinase|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Cytoskeleton […]

For research use only. We do not sell to patients. Cerulenin CAS No. : 17397-89-6 Biological Activity：Cerulenin, a potent, natural inhibitor of fatty acid synthase (FASN), is an epoxide produced by the fungus Cephalosporium caeruleus. Cerulenin inhibits topoisomerase I catalytic activity and augments SN-38-induced apoptosis. Cerulenin has antifungal and antitumor activies[2][3][4]. Research Area：Infection|Metabolic Disease Targets：Fungal|Fatty […]