Tag: Inhibitor|Inducer

For research use only. We do not sell to patients. Pirarubicin Hydrochloride CAS No. : 95343-20-7 Biological Activity：Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors. Research Area：Cancer|Infection Targets：Topoisomerase|Autophagy|Bacterial|Antibiotic Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. GDC-0623 CAS No. : 1168091-68-6 Biological Activity：GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM). Research Area：Cancer Targets：MEK|Apoptosis Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. Gefitinib (GMP) CAS No. : 184475-35-2 Biological Activity：Gefitinib (ZD1839) (GMP) is Gefitinib (HY-50895) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Gefitinib is a potent, selective and orally active EGFR tyrosine kinase inhibitor[2]. Research Area：Cancer […]

For research use only. We do not sell to patients. Linagliptin-d4 CAS No. : 2140263-92-7 Biological Activity：Linagliptin-d4 is deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Research Area：Metabolic Disease Targets：Ferroptosis|Autophagy|Dipeptidyl Peptidase Related Small Molecules:CIL56;DB0614;Ciclopirox-d11;Ciclopirox olamine;Curcumin;Cofrogliptin;(-)-Epicatechin;Eugenol-d3;Artemisinin-d3;MMRi62;Anagliptin-d6;UAMC-3203;L-Glutamic acid-15N,d5;Chalcones A-N-5;Pifithrin-β hydrobromide;PD146176;Roxadustat;P32/98;Matrine;Liproxstatin-1;Hemin Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. Antitumor agent-43 Biological Activity：Antitumor agent-43 (Compound 4B) is a potent antitumor agent, with an IC50of 0.5 µM for (T-24 cell). Antitumor agent-43 (Compound 4B) induces cell cycle arrest at G2/M phase. Research Area：Cancer Targets：DNA/RNA Synthesis|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Ametantrone;BJE6-106;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor […]

For research use only. We do not sell to patients. SN-38-d3 CAS No. : 718612-49-8 Biological Activity：SN-38-d3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively[2][3][4]. Research Area：Cancer Targets：Topoisomerase|Autophagy|ADC Cytotoxin Related Small […]

For research use only. We do not sell to patients. Dictamine CAS No. : 484-29-7 Biological Activity：Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi. IC50 value: Target: Dictamnine has antimicrobial activities against […]

For research use only. We do not sell to patients. Clitocine CAS No. : 105798-74-1 Biological Activity：Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can […]

For research use only. We do not sell to patients. BTZO-1 CAS No. : 99420-15-2 Biological Activity：BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro. […]

For research use only. We do not sell to patients. Oncrasin-1 CAS No. : 75629-57-1 Biological Activity：Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations; also led to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant […]