Tag: Inhibitor|Inducer

For research use only. We do not sell to patients. DD1 CAS No. : 187585-11-1 Biological Activity：DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. DD1 induces apoptosis in the caspase-dependent manner. DD1 induces mitochondrial membrane depolarization and Bad dephosphorylation. Research Area：Cancer Targets：Ribosomal S6 Kinase (RSK)|Proteasome|Apoptosis Related Small Molecules:Physalin […]

For research use only. We do not sell to patients. Methylstat CAS No. : 1310877-95-2 Biological Activity：Methylstat is a potent histone demethylases inhibitor. Methylstat shows anti-proliferative activity with low cytotoxicity. Methylstat induces apoptosis and cell cycle arrest at G0/G1 phase. Methylstat increases the expression of p53 and p21 protein levels. Methylstat inhibits angiogenesis induced by […]

For research use only. We do not sell to patients. EGFR-IN-11 CAS No. : 2463200-44-2 Biological Activity：EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM for triple mutant EGFRL858R/T790M/C797S. EGFR-IN-11 significantly suppresses the EGFR phosphorylation, induce the apoptosis, and arrest cell cycle at G0/G1. Research Area：Cancer Targets：EGFR|Apoptosis Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. CHMFL-ABL/KIT-155 CAS No. : 2081093-21-0 Biological Activity：CHMFL-ABL/KIT-155 (CHMFL-ABL-KIT-155; compound 34) is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s of 46 nM and 75 nM, respectively), and it also presents significant inhibitory activities to BLK (IC50=81 nM), CSF1R (IC50=227 nM), […]

For research use only. We do not sell to patients. Prexasertib CAS No. : 1234015-52-1 Biological Activity：Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of

For research use only. We do not sell to patients. Tubulin polymerization-IN-9 CAS No. : 2485020-93-5 Biological Activity：Tubulin polymerization-IN-9 is a potent tubulin inhibitor with IC50 of 1.82 μM. Tubulin polymerization-IN-9 causes cell cycle arrest at G2/M phase, and induces cell apoptosis and depolarized mitochondria of K562 cells. Tubulin polymerization-IN-9 has potent anti-vascular and antitumor […]

For research use only. We do not sell to patients. Furazolidone-d4 CAS No. : 1217222-76-8 Biological Activity：Furazolidone-d4 is deuterium labeled Furazolidone. Research Area：Infection Targets：Bacterial|Antibiotic|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;BJE6-106;Dinaciclib;Antibacterial agent 99;Ecteinascidin 770;MDM2-p53-IN-15 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  […]

For research use only. We do not sell to patients. Griseofulvin-d3 CAS No. : 1279033-22-5 Biological Activity：Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal drug[2]. Research Area：Infection|Cancer Targets：Fungal|Antibiotic|Endogenous Metabolite|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Antifungal agent 20;Physalin A;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;Bomedemstat ditosylate;2-Mercaptobenzothiazole;Sandramycin;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Enpp/Carbonic […]

For research use only. We do not sell to patients. Deoxypodophyllotoxin CAS No. : 19186-35-7 Biological Activity：Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology not only as anti-mitotics but also as potent inhibitors […]

For research use only. We do not sell to patients. UBX1325 CAS No. : 2271269-01-1 Biological Activity：UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic […]