Tag: Inhibitor|Agonist

For research use only. We do not sell to patients. Indole-3-carbinol CAS No. : 700-06-1 Biological Activity：Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1). Research Area：Cancer Targets：NF-κB|Endogenous Metabolite|E1/E2/E3 Enzyme|Aryl Hydrocarbon Receptor Related Screening Libraries:Natural Product Library Plus;Drug Repurposing […]

For research use only. We do not sell to patients. Reproterol CAS No. : 54063-54-6 Biological Activity：Reproterol is a dual acting β2-adrenoceptor agonist and PDE inhibitor. The theophylline constituent of Reproterol inhibits phosphodiesterase activity induced by adenylyl cyclase. Reproterol has the potential for asthma research[2]. Research Area：Inflammation/Immunology Targets：Phosphodiesterase (PDE)|Adrenergic Receptor Related Small Molecules:Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;ATX inhibitor 22;Carbazeran citrate;Todralazine;ARC 239 […]

For research use only. We do not sell to patients. Quinagolide hydrochloride CAS No. : 94424-50-7 Biological Activity：Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used […]

For research use only. We do not sell to patients. KIN1408 CAS No. : 1903800-11-2 Biological Activity：KIN1408 is an agonist of the RIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity against HCV, influenza A, dengue virus 2, Ebola, Nipah, and Lassa viruses[2]. Research Area：Infection Targets：HCV|Influenza Virus Related Screening Libraries:Bioactive Compound […]

For research use only. We do not sell to patients. Methylprednisolone-d5 Biological Activity：Methylprednisolone-d5 (U 7532-d5) is the deuterium labeled Methylprednisolone. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[3]. Research Area：Cancer|Infection|Endocrinology|Inflammation/Immunology Targets：Autophagy|Glucocorticoid Receptor|SARS-CoV Related Small Molecules:Deflazacort-D5;SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;INSCoV-614(1B);Anti-SARS-CoV-2 Spike […]

For research use only. We do not sell to patients. Simpinicline CAS No. : 753015-44-0 Biological Activity：Simpinicline (OC-02), a highly selective nicotinic acetylcholine receptor (nAChR) agonist, shows potent antiviral activity against the SARS-CoV-2 variants in cell culture with an IC50 of 0.04 µM. Research Area：Infection Targets：nAChR|SARS-CoV Related Small Molecules:Spinosad;Pyrantel;SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;NS 9283;Ketotifen fumarate;Myosmine-d4;SARS-CoV-2-IN-16;Thapsigargin;Benzethonium chloride;INSCoV-614(1B);Dihydro-β-erythroidine;A-867744;Catestatin;Anti-SARS-CoV-2 […]

For research use only. We do not sell to patients. Gardiquimod diTFA CAS No. : 1159840-61-5 Biological Activity：Gardiquimod diTFA, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specifically activates TLR7 when used at concentrations below 10 μM[2]. Research Area：Cancer|Infection Targets：HIV|Toll-like […]

For research use only. We do not sell to patients. Hydrocortisone phosphate CAS No. : 3863-59-0 Biological Activity：Hydrocortisone phosphate (Hydrocortisone 21-phosphate), a physiological glucocorticoid, and is an orally active steroidal anti-inflammatory drug (SAID). Hydrocortisone phosphate inhibits proinflammatory cytokine activity, with IC50s of 6.7 and 21.4 μM for IL-6 and IL-3, respectively. Hydrocortisone phosphate can be […]