Tag: Inhibitor|Agonist

For research use only. We do not sell to patients. Zidovudine-13C,d3 Biological Activity：Zidovudine-13C,d3 is the 13C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Research Area：Infection Targets：CRISPR/Cas9|HIV Related Small Molecules:HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine;Islatravir;HIV-1 […]

For research use only. We do not sell to patients. Pyrantel pamoate CAS No. : 22204-24-6 Biological Activity：Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections […]

For research use only. We do not sell to patients. Loratadine-d4 CAS No. : 381727-27-1 Biological Activity：Loratadine-d4 (Loratidine-d4) is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators. Research Area：Infection|Endocrinology|Inflammation/Immunology Targets：Influenza […]

For research use only. We do not sell to patients. ADL-5859 CAS No. : 850173-95-4 Biological Activity：ADL-5859 (compound 20) is a selective and orally active δ opioid receptor (DOR) agonist with an Ki and an EC50 value of 0.84 and 20 nM, respectively. ADL-5859 also shows inhibitory activity to hERG channel with an IC50 value […]

For research use only. We do not sell to patients. L-Glutamine-13C5,15N2 CAS No. : 285978-14-5 Biological Activity：L-Glutamine-13C5,15N2 (L-Glutamic acid 5-amide-13C5,15N2) is the 13C- and 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in […]

For research use only. We do not sell to patients. Galanthamine hydrobromide CAS No. : 1953-04-4 Biological Activity：Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC50 of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α3β4, α4β2, α6β4 nicotinic receptors ( nAChRs). Galanthamine hydrobromide […]

For research use only. We do not sell to patients. Resiquimod CAS No. : 144875-48-9 Biological Activity：Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Research Area：Inflammation/Immunology|Cancer Targets：HCV|Toll-like Receptor (TLR) Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library […]

For research use only. We do not sell to patients. D-Cycloserine CAS No. : 68-41-7 Biological Activity：D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research[2]. Research Area：Infection|Neurological Disease|Cancer Targets：Bacterial|Antibiotic|iGluR Related Screening Libraries:Covalent […]

For research use only. We do not sell to patients. Anatabine dicitrate Biological Activity：Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. Anatabine dicitrate is a potent α4β2 nAChR agonist. Anatabine dicitrate inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory […]

For research use only. We do not sell to patients. Hydrocortisone hemisuccinate CAS No. : 2203-97-6 Biological Activity：Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti-inflammatory drug (SAID). Hydrocortisone hemisuccinate inhibits proinflammatory cytokine activity, with IC50s of 6.7 and 21.4 μM for IL-6 and IL-3, respectively. Hydrocortisone hemisuccinate can be used […]