Tag: Inhibitor|Agonist

For research use only. We do not sell to patients. Ca2+ channel agonist 1 CAS No. : 1402821-24-2 Biological Activity：Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal […]

For research use only. We do not sell to patients. Tulobuterol hydrochloride CAS No. : 56776-01-3 Biological Activity：Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle […]

For research use only. We do not sell to patients. (R)-(+)-Anatabine CAS No. : 126454-22-6 Biological Activity：(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent α4β2 nAChR agonist. Anatabine inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine has anti-inflammatory effects and has the […]

For research use only. We do not sell to patients. Naluzotan CAS No. : 740873-06-7 Biological Activity：Naluzotan is a novel, potent, and selective amidosulfonamide 5-HT1A agonist with IC50 and Ki of appr 20 nM and 5.1 nM, used for the treatment of anxiety and depression; Also a weak hERG K+ channel blocker, with IC50 of […]

For research use only. We do not sell to patients. Mesalamine impurity P CAS No. : 887256-40-8 Biological Activity：Mesalamine impurity P is an impurity of Mesalamine (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. Research Area：Cancer|Inflammation/Immunology Targets：PAK|NF-κB|PPAR Related Small Molecules:Akt/NF-κB/JNK-IN-1;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;GNE 2861;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside […]

For research use only. We do not sell to patients. Guanabenz CAS No. : 5051-62-7 Biological Activity：Guanabenz is an orally active α-2-adrenoceptor agonist. Guanabenz has antihypertensive effect and antiparasitic activity. Guanabenz interferes ER stress-signalling and has protective effects in cardiac myocytes. Guanabenz also is used for the research of high blood pressure[2][3]. Research Area：Cardiovascular Disease […]

For research use only. We do not sell to patients. Dynorphin A (1-10) CAS No. : 79994-24-4 Biological Activity：Dynorphin A (1-10) an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM. Research Area：Neurological Disease Targets：Opioid Receptor|iGluR Related Small Molecules:ORL1 […]

For research use only. We do not sell to patients. Methylprednisolone-d4 Biological Activity：Methylprednisolone-d4 is deuterium labeled Methylprednisolone. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[3]. Research Area：Cancer|Infection|Endocrinology|Inflammation/Immunology Targets：Autophagy|Glucocorticoid Receptor|SARS-CoV Related Small Molecules:Deflazacort-D5;SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;INSCoV-614(1B);Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;Glucocorticoid receptor […]

For research use only. We do not sell to patients. Cefminox sodium CAS No. : 75498-96-3 Biological Activity：Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity. Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits […]

For research use only. We do not sell to patients. Leelamine hydrochloride CAS No. : 16496-99-4 Biological Activity：Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells […]