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(R)-(+)-Anatabine
CAS No. : 126454-22-6
Biological Activity：(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent α4β2 nAChR agonist. Anatabine inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment[2][3][4].
Research Area：Inflammation/Immunology|Neurological Disease
Targets：nAChR|NF-κB|Amyloid-β
Related Small Molecules:β-Amyloid (13-27);Akt/NF-κB/JNK-IN-1;Icariside F2;Saikosaponin C;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;β-Amyloid (1-42), (rat/mouse) (TFA);Spinosad;ALPK1-IN-1;Regaloside A;β-Amyloid (12-28) (TFA);Pyrantel;IMD-ferulic;SN52;BuChE-IN-5;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;MDR-1339;Licochalcone D;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine
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