Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Lidocaine hydrochloride hydrate CAS No. : 6108-05-0 Biological Activity：Lidocaine (Lignocaine) hydrochloride hydrate inhibits sodium channels involving complex voltage and using dependence. Lidocaine hydrochloride hydrate decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling […]

For research use only. We do not sell to patients. Tacrolimus monohydrate CAS No. : 109581-93-3 Biological Activity：Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. Research Area：Cancer|Infection|Inflammation/Immunology Targets：FKBP|Autophagy|Bacterial|Antibiotic|Phosphatase Related Screening Libraries:Covalent Screening […]

For research use only. We do not sell to patients. Lacidipine-d10 CAS No. : 1185245-62-8 Biological Activity：Lacidipine-d10 is the deuterium labeled Lacidipine. Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker[2]. Research Area：Cardiovascular Disease Targets：Calcium Channel|Reactive Oxygen Species|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Bomedemstat ditosylate;Chitoheptaose heptahydrochloride;Enpp/Carbonic anhydrase-IN-1;GK563;Benidipine hydrochloride;Calpeptin;Lobetyolin;CaV1.3 antagonist-1;14-Deoxyandrographolide;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CYPMPO;Xevinapant;Mangiferin Trending products：Recombinant […]

For research use only. We do not sell to patients. Solamargine CAS No. : 20311-51-7 Biological Activity：Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 […]

For research use only. We do not sell to patients. CDK4/6-IN-10 CAS No. : 2688098-11-3 Biological Activity：CDK4/6-IN-10 is a potent, selective and orally active CDK4 and CDK6 inhibitor with IC50s of 22 nM and 10 nM, respectively. CDK4/6-IN-10 shows antitumor activity. CDK4/6-IN-10 has the potential for the research of Multiple myeloma (MM). Research Area：Cancer Targets：CDK|Apoptosis […]

For research use only. We do not sell to patients. Picropodophyllotoxin-d6 Biological Activity：Picropodophyllotoxin-d6 is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM. Research Area：Cancer|Endocrinology Targets：IGF-1R|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Orlistat CAS No. : 96829-58-2 Biological Activity：Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity. Anti-atherosclerotic effect[2]. Research Area：Metabolic Disease|Cancer Targets：Fatty Acid Synthase (FASN)|Apoptosis Related Screening […]

For research use only. We do not sell to patients. Cytostatin CAS No. : 682329-63-1 Biological Activity：Cytostatin is a potent and selective inhibitor of PP2A with promising antitumor activity. Cytostatin is also an inhibitor of cell adhesion to extracellular matrix and induces cell apoptosis. Cytostatin belongs to the fostriecin family of natural products[2][3]. Research Area：Cancer […]

For research use only. We do not sell to patients. K858 (Racemic) CAS No. : 72926-24-0 Biological Activity：K858 Racemic is an ATP-uncompetitive inhibitor of kinesin Eg5 with an IC50 of 1.3 μM. Research Area：Cancer Targets：Kinesin|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cytoskeleton Compound Library;Targeted Diversity Library; […]

For research use only. We do not sell to patients. PI3K/AKT-IN-2 CAS No. : 2684412-41-5 Biological Activity：PI3K/AKT-IN-2 (Compound 12c) is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis. PI3K/AKT-IN-2 inhibits the polymerization of tubulin. Research Area：Cancer Targets：Akt|Microtubule/Tubulin|MMP|Apoptosis|PI3K Related Small Molecules:Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Umbralisib hydrochloride;Tirbanibulin dihydrochloride;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Tilavonemab;Mangiferin;Cambinol;Antioxidant […]