Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Afatinib dimaleate CAS No. : 850140-73-7 Biological Activity：Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and […]

For research use only. We do not sell to patients. Benzyl isothiocyanate CAS No. : 622-78-6 Biological Activity：Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity[2]. Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells[2]. Research Area：Cancer|Endocrinology Targets：Parasite|Bacterial|Antibiotic|Apoptosis Related Screening Libraries:Natural Product Library […]

For research use only. We do not sell to patients. Piceatannol CAS No. : 10083-24-6 Biological Activity：Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI). Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and […]

For research use only. We do not sell to patients. Moexipril CAS No. : 103775-10-6 Biological Activity：Moexipril is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril exhibits antihypertensive and neuroprotective effects–[4]. Research Area：Neurological Disease|Cardiovascular Disease Targets：Angiotensin-converting Enzyme (ACE)|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase […]

For research use only. We do not sell to patients. EGFR-IN-52 CAS No. : 454436-75-0 Biological Activity：EGFR-IN-52 (Compound 4) is a potent EGFR inhibitor with IC50 values of 0.358, 86.02 and 432.67 µM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-52 shows cytotoxic activity against cancer cell lines and induces apoptosis. Research Area：Cancer Targets：EGFR|Apoptosis […]

For research use only. We do not sell to patients. NVS-CECR2-1 CAS No. : 1992047-61-6 Biological Activity：NVS-CECR2-1, a non-BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity (IC50=47 nM; KD=80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces […]

For research use only. We do not sell to patients. Droxinostat CAS No. : 99873-43-5 Biological Activity：Droxinostat (NS 41080) is a histone deacetylase (HDAC) inhibitor. Droxinostat selectively inhibits HDAC3, HDAC6, and HDAC8 with IC50 values of 16.9 μM, 2.47 μM, and 1.46 μM, respectively. Droxinostat can be used for the research of hepatocellular carcinoma (HCC)[2]. […]

For research use only. We do not sell to patients. Ispinesib CAS No. : 336113-53-2 Biological Activity：Ispinesib is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM. Research Area：Cancer Targets：Kinesin|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Anti-Cancer […]

For research use only. We do not sell to patients. MK-5108 CAS No. : 1010085-13-8 Biological Activity：MK-5108 is a highly potent and specific inhibitor of Aurora A kinase with an IC50 value of 0.064 nM. Research Area：Cancer Targets：Autophagy|Aurora Kinase Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Kinase Inhibitor […]

For research use only. We do not sell to patients. SU11652 CAS No. : 326914-10-7 Biological Activity：SU11652 is a potent receptor tyrosine kinase (RTK) inhibitor. SU11652 also inhibits several members of the split kinase family of RTKs, including VEGFR, FGFR, PDGFR, and Kit. SU11652 can be uesd for spontaneous cancers expressing Kit mutations research. Research […]