Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. CR-1-31-B CAS No. : 1352914-52-3 Biological Activity：CR-1-31-B is a synthetic rocaglate and a potent eIF4A inhibitor. CR-1-31-B exhibits powerful inhibitory effects over eIF4A by perturbing the interaction between eIF4A and RNA, sequentially impeding initiation during protein synthesis. CR-1-31-B perturbs association of Plasmodium falciparum eIF4A (PfeIF4A) […]

For research use only. We do not sell to patients. Anti-inflammatory agent 21 CAS No. : 2408836-40-6 Biological Activity：Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory […]

For research use only. We do not sell to patients. Silmitasertib CAS No. : 1009820-21-6 Biological Activity：Silmitasertib (CX-4945) is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α’. Research Area：Cancer Targets：Autophagy|Casein Kinase Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell […]

For research use only. We do not sell to patients. XMU-MP-3 CAS No. : 2031152-08-4 Biological Activity：XMU-MP-3 is a potent non-covalent BTK inhibitor with IC50s of 10.7 nM and 17.0 nM for BTK WT and BTK C481S mutation in the presence of 10 μM ATP, respectively. XMU-MP-3 also induces apoptosis. Research Area：Cancer Targets：Btk|Apoptosis Related Screening […]

For research use only. We do not sell to patients. Ginsenoside Rk1 CAS No. : 494753-69-4 Biological Activity：Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures. Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB[2]. Ginsenoside Rk1 has anti-tumor effect, […]

For research use only. We do not sell to patients. Rohinitib CAS No. : 1139253-73-8 Biological Activity：Rohinitib is a potent and specific eIF4A inhibitor. Rohinitib induces cell apoptosis of acute myeloid leukemia (AML) cell lines and reduces the leukemia burden of AML xenograft model. Rohinitib can be used for the research of AML. Research Area：Cancer […]

For research use only. We do not sell to patients. PluriSIn 1 CAS No. : 91396-88-2 Biological Activity：PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-coA desaturase (SCD), and is a pluripotent cell-specific inhibitor. Research Area：Cancer Targets：Stearoyl-CoA Desaturase (SCD)|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound […]

For research use only. We do not sell to patients. Aphidicolin CAS No. : 38966-21-1 Biological Activity：Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex […]

For research use only. We do not sell to patients. Moexipril-d5 CAS No. : 1356929-49-1 Biological Activity：Moexipril-d5 is the deuterium labeled Moexipril. Moexipril hydrochloride is a potent orally active non-sulfhydryl angiotensin converting enzyme(ACE) inhibitor, which is used for the treatment of hypertension and congestive heart failure[2]. Research Area：Cardiovascular Disease Targets：Angiotensin-converting Enzyme (ACE)|Apoptosis Related Small Molecules:Physalin […]

For research use only. We do not sell to patients. Tanespimycin CAS No. : 75747-14-7 Biological Activity：Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90[5]. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin […]