Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Nimodipine-d7 CAS No. : 1246815-36-0 Biological Activity：Nimodipine-d7 is the deuterium labeled Nimodipine. Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders. Research Area：Cardiovascular Disease|Cancer Targets：Autophagy|Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM […]

For research use only. We do not sell to patients. Pracinostat-d7 CAS No. : 1795137-15-3 Biological Activity：Pracinostat-d7 is the deuterium labeled Pracinostat. Pracinostat is a potent histone deacetylase (HDAC) inhibitor, with IC50s of 40-140 nM, used for cancer research[2]. Research Area：Cancer Targets：HDAC|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine […]

For research use only. We do not sell to patients. Thiamine-d4 hydrochloride Biological Activity：Thiamine-d4 (hydrochloride) is deuterium labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes. Research Area：Neurological Disease Targets：HBV|Endogenous Metabolite|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;Bomedemstat ditosylate;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Enpp/Carbonic anhydrase-IN-1;Biliverdin […]

For research use only. We do not sell to patients. BIO-acetoxime CAS No. : 667463-85-6 Biological Activity：BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity. Research Area：Infection|Inflammation/Immunology|Neurological Disease Targets：HSV|GSK-3|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase […]

For research use only. We do not sell to patients. Tubulin polymerization-IN-3 Biological Activity：Tubulin polymerization-IN-3 (compound 4c) is a potent tubulin polymerization inhibitor, with an IC50 of 3.84 µM. Tubulin polymerization-IN-3 can induce apoptosis in colon cancer cells. Research Area：Cancer Targets：Microtubule/Tubulin|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Tirbanibulin dihydrochloride;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Tilavonemab;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine […]

For research use only. We do not sell to patients. Irinotecan-d10 CAS No. : 718613-28-6 Biological Activity：Irinotecan-d10 ((+)-Irinotecan-d10) is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. Research Area：Cancer Targets：Topoisomerase|Autophagy Related Small Molecules:Gepotidacin;Topoisomerase I/II inhibitor 3;(R)-Camptothecin-d5;Topoisomerase II inhibitor 8;FLT3-IN-13;TP3011;TAS-103 […]

For research use only. We do not sell to patients. Mitoxantrone diacetate CAS No. : 70711-41-0 Biological Activity：Mitoxantrone diacetate is a potent topoisomerase II inhibitor. Mitoxantrone diacetate also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone diacetate induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone diacetate shows antitumor activity[2][3][4]. […]

For research use only. We do not sell to patients. CGI-1746 CAS No. : 910232-84-7 Biological Activity：CGI-1746 is a potent and highly selective inhibitor of the Btk with IC50 of 1.9 nM. Research Area：Inflammation/Immunology Targets：Autophagy|Btk Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Autophagy Compound Library;Pyroptosis Compound Library;Chemical Probe Library;Anti-Blood Cancer Compound Library; Related […]

For research use only. We do not sell to patients. c-Met-IN-10 CAS No. : 2415291-03-9 Biological Activity：c-Met-IN-10 (compound 26a) is a highly potent c-Met kinase inhibitor with an IC50 value of 16 nM. c-Met-IN-10 has inhibitory activity against cancer cells A549, H460 and HT-29 with IC50s of 0.56 ~ 1.59 μM. c-Met-IN-10 suppresses the colony […]

For research use only. We do not sell to patients. Tizoxanide D4 CAS No. : 1246817-56-0 Biological Activity：Tizoxanide D4 (TIZ D4) is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[2]. Research Area：Infection Targets：Autophagy|HIV|Bacterial […]