Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. (±)-Evodiamine CAS No. : 518-18-3 Biological Activity：(±)-Evodiamine, a quinazolinocarboline alkaloid, is a Top1 inhibitor. Evodiamine exhibits anti-inflammatory, antiobesity, and antitumor effects. (±)-Evodiamine inhibits the proliferation of a wide variety of tumor cells by inducing their apoptosis. Research Area：Cancer|Inflammation/Immunology|Cardiovascular Disease Targets：Topoisomerase|Apoptosis Related Screening Libraries:Natural Product Library […]

For research use only. We do not sell to patients. Dubermatinib CAS No. : 1341200-45-0 Biological Activity：Dubermatinib (TP-0903) is a potent and selective Axl receptor tyrosine kinase inhibitor with an IC50 value of 27 nM. Research Area：Cancer Targets：Apoptosis|TAM Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Kinase Inhibitor […]

For research use only. We do not sell to patients. Meloxicam sodium CAS No. : 71125-39-8 Biological Activity：Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively. Research Area：Cancer|Inflammation/Immunology Targets：Autophagy|MMP|Apoptosis|COX Related Small Molecules:Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;COX-2/5-LOX-IN-3;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer […]

For research use only. We do not sell to patients. Nitidine chloride CAS No. : 13063-04-2 Biological Activity：Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway. […]

For research use only. We do not sell to patients. Lestaurtinib CAS No. : 111358-88-4 Biological Activity：Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC50s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, […]

For research use only. We do not sell to patients. (rel)-Atorvastatin CAS No. : 110862-48-1 Biological Activity：(rel)-Atorvastatin, a relative configuration of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively[2][3]. Research […]

For research use only. We do not sell to patients. Betulin CAS No. : 473-98-3 Biological Activity：Betulin (Trochol), is a sterol regulatory element-binding protein (SREBP) inhibitor with an IC50 of 14.5 μM in K562 cell line. Research Area：Cancer Targets：Fatty Acid Synthase (FASN)|Endogenous Metabolite|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound […]

For research use only. We do not sell to patients. Cryptotanshinone CAS No. : 35825-57-1 Biological Activity：Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM. Research Area：Cancer Targets：Autophagy|STAT Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound […]

For research use only. We do not sell to patients. Quinidine Monosulfate CAS No. : 50-54-4 Biological Activity：Quinidine Monosulfate is an antiarrhythmic agent. Quinidine Monosulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine Monosulfate is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinidine Monosulfate can […]

For research use only. We do not sell to patients. Sterigmatocystine CAS No. : 10048-13-2 Biological Activity：Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor[2]. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in […]