Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. NSC697923 CAS No. : 343351-67-7 Biological Activity：NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by […]

For research use only. We do not sell to patients. Letrozole CAS No. : 112809-51-5 Biological Activity：Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer[2][3]. Research Area：Cancer Targets：Autophagy|Aromatase […]

For research use only. We do not sell to patients. Lidocaine CAS No. : 137-58-6 Biological Activity：Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative […]

For research use only. We do not sell to patients. Flurbiprofen-d3 CAS No. : 1185133-81-6 Biological Activity：Flurbiprofen-d3 (dl-Flurbiprofen-d3) is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen […]

For research use only. We do not sell to patients. Verubulin CAS No. : 827031-83-4 Biological Activity：Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types. Research Area：Cancer Targets：Microtubule/Tubulin|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. GGTI298 CAS No. : 180977-44-0 Biological Activity：GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively. Research Area：Cancer […]

For research use only. We do not sell to patients. Dextran sulfate sodium salt (MW 4500-5500) CAS No. : 9011-18-1 Biological Activity：Dextran sulfate sodium salt (MW 4500-5500) is a is a polymer of anhydroglucose with the molecular weight range of 4500-5500. Dextran sulfate sodium salt inhibits the replication of the human immunodeficiency virus by preventing […]

For research use only. We do not sell to patients. Kaempferide CAS No. : 491-54-3 Biological Activity：Kaempferide is an O-methylated flavonol, a type of chemical compound. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4′-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adenosyl-L-homocysteine and kaempferide. P-glycoproteins. Kaempferide has antiviral activities. Research Area：Cancer|Infection […]

For research use only. We do not sell to patients. Cobimetinib-d4 Biological Activity：Cobimetinib-d4 (GDC-0973-d4) is the deuterium labeled Cobimetinib. Cobimetinib (GDC-0973, RG7420) is a potent, selective and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1. Research Area：Cancer Targets：MEK|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Avutometinib;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10 […]

For research use only. We do not sell to patients. Moexipril hydrochloride CAS No. : 82586-52-5 Biological Activity：Moexipril hydrochloride (RS-10085) is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril hydrochloride exhibits antihypertensive and neuroprotective effects–[4]. Research Area：Cardiovascular Disease Targets：Angiotensin-converting Enzyme (ACE)|Apoptosis Related Screening Libraries:Drug Repurposing […]