Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Brevilin A CAS No. : 16503-32-5 Biological Activity：Brevilin A is an orally active STAT3/JAK inhibitor (STAT3 IC50= 10.6 µM). Brevilin A shows anti-tumor activity, anti-proliferative activity to cancer cells, and can induce apoptosis and autophagy[2]. Research Area：Cancer Targets：JAK|Autophagy|STAT|Apoptosis Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library […]

For research use only. We do not sell to patients. Cytarabine CAS No. : 147-94-4 Biological Activity：Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity. Research Area：Cancer|Infection Targets：HSV|Nucleoside Antimetabolite/Analog|Autophagy|Orthopoxvirus|DNA/RNA Synthesis|Endogenous […]

For research use only. We do not sell to patients. Letrozole-d4 CAS No. : 1133712-96-5 Biological Activity：Letrozole-d4 (CGS 20267-d4) is the deuterium labeled Letrozole. Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for […]

For research use only. We do not sell to patients. Carvedilol phosphate hemihydrate CAS No. : 610309-89-2 Biological Activity：Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is a non-selective β/α-1 blocker. Carvedilol phosphate hemihydrate inhibits lipid peroxidation with an IC50 of 5 μM. Carvedilol phosphate hemihydrate is a multiple action antihypertensive agent with potential use in […]

For research use only. We do not sell to patients. Bergenin CAS No. : 477-90-7 Biological Activity：Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties[2]. Research Area：Cancer|Infection|Inflammation/Immunology Targets：Fungal|Autophagy|Bacterial|Apoptosis|Virus Protease Related Screening Libraries:Natural Product Library Plus;Drug Repurposing […]

For research use only. We do not sell to patients. Estramustine phosphate sodium CAS No. : 52205-73-9 Biological Activity：Estramustine phosphate sodium, an estradiol analog, is an orally active antimicrotubule chemotherapy agent. Estramustine phosphate sodium depolymerises microtubules by binding to microtubule associated proteins (MAPs) and/or to tubulin. Estramustine phosphate sodium can interfere mitosis, trigger cell death […]

For research use only. We do not sell to patients. Glibenclamide CAS No. : 10238-21-8 Biological Activity：Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic […]

For research use only. We do not sell to patients. Astragalin CAS No. : 480-10-4 Biological Activity：Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis. Research Area：Cancer|Infection|Inflammation/Immunology Targets：NF-κB|Apoptosis Related Screening […]

For research use only. We do not sell to patients. Zn(BQTC) Biological Activity：Zn(BQTC) is a highly potent mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) inhibitor. Zn(BQTC) causes severe damage to the mtDNA and nDNA, sequentially disruptes mitochondrial and nuclear functions. Zn(BQTC) promotes the DNA damage-induced apoptotic signaling pathway. Zn(BQTC) has selectively antiproliferative activity against A549R […]

For research use only. We do not sell to patients. Furazolidone CAS No. : 67-45-8 Biological Activity：Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. Target: Antibacterial Furazolidone is a novel therapeutic strategy in AML patients. Furazolidone can Inhibit the bone-marrow transformation mediated by […]