Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Propylparaben sodium CAS No. : 35285-69-9 Biological Activity：Propylparaben sodium (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben sodium is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben sodium disrupts antral follicle growth and steroidogenic function by altering […]

For research use only. We do not sell to patients. c-Met-IN-14 CAS No. : 2443380-34-3 Biological Activity：c-Met-IN-14 (compound 26af) is a selective inhibitor of c-Met kinase from N-sulfonylamidine-based derivatives, with an IC50 value of 2.89 nM. c-Met-IN-14 shows anticancer activity by blocking phosphorylation of c-Met, and arrests cell cycle at G2/M phase. c-Met-IN-14 induces apoptosis […]

For research use only. We do not sell to patients. SB 216763 CAS No. : 280744-09-4 Biological Activity：SB 216763 is potent, selective and ATP-competitive GSK-3 inhibitor with IC50s of 34.3 nM for both GSK-3α and GSK-3β. Research Area：Neurological Disease|Cancer Targets：Autophagy|GSK-3 Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound […]

For research use only. We do not sell to patients. p38 MAPK-IN-3 Biological Activity：p38 MAPK-IN-3 (Compound 2c) is a p38α MAPK inhibitor. p38 MAPK-IN-3 has antitumor activities and induces apoptosis and ROS. Research Area：Cancer Targets：p38 MAPK|Reactive Oxygen Species|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Bomedemstat ditosylate;Chitoheptaose heptahydrochloride;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CYPMPO;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9 Trending […]

For research use only. We do not sell to patients. Quinidine polygalacturonate CAS No. : 27555-34-6 Biological Activity：Quinidine polygalacturonate is an antiarrhythmic agent. Quinidine polygalacturonate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine polygalacturonate is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinidine polygalacturonate can […]

For research use only. We do not sell to patients. Flurbiprofen-d5 CAS No. : 215175-76-1 Biological Activity：Flurbiprofen-d5 (dl-Flurbiprofen-d5) is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen […]

For research use only. We do not sell to patients. Mitoxantrone CAS No. : 65271-80-9 Biological Activity：Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity[2][3][4]. Mitoxantrone also has anti-orthopoxvirus activity […]

For research use only. We do not sell to patients. Alphitolic acid CAS No. : 19533-92-7 Biological Activity：Alphitolic acid (Aophitolic acid) is an anti-inflammatory triterpene could found in quercus aliena. Alphitolic acid blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic […]

For research use only. We do not sell to patients. Pracinostat CAS No. : 929016-96-6 Biological Activity：Pracinostat is a potent histone deacetylase (HDAC) inhibitor, with IC50s of 40-140 nM, used for cancer research. Pracinostat also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC50 below 10 nM[4]. Research Area：Cancer Targets：HDAC|Apoptosis Related Screening Libraries:Covalent Screening […]

For research use only. We do not sell to patients. Capecitabine-d11 CAS No. : 1132662-08-8 Biological Activity：Capecitabine-d11 is the deuterium labeled Capecitabine. Capecitabine is an oral prodrug that is converted to its active metabolite, 5-FU, by thymidine phosphorylase[2]. Research Area：Cancer Targets：Nucleoside Antimetabolite/Analog|DNA/RNA Synthesis|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;m7GpppCpG;Ametantrone;BJE6-106;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5 […]