Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Asiatic acid CAS No. : 464-92-6 Biological Activity：Asiatic acid, a pentacyclic triterpene found in Centella asiatica, induces apoptosis in melanoma cells. Asiatic acid has the potential for skin cancer treatment. Asiatic acid also has anti-inflammatory activities[2]. Research Area：Cancer|Inflammation/Immunology Targets：Parasite|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive […]

For research use only. We do not sell to patients. alpha-Mangostin CAS No. : 6147-11-1 Biological Activity：alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. Research Area：Cancer Targets：Fungal|Reactive Oxygen Species|Bacterial|Apoptosis|Virus […]

For research use only. We do not sell to patients. Triptolide CAS No. : 38748-32-2 Biological Activity：Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor[2][3][4][5][6]. Research Area：Cancer Targets：NF-κB|Apoptosis Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Drug Repurposing Compound […]

For research use only. We do not sell to patients. Acetylcysteine CAS No. : 616-91-1 Biological Activity：Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases[5]. Acetylcysteine induces cell […]

For research use only. We do not sell to patients. Topo I-IN-1 Biological Activity：Topo I-IN-1 (Compound 14d) is a potent Topo I inhibitor with antitumor activity and DNA intercalative capability. Topo I-IN-1 induces cell apoptosis. Research Area：Cancer Targets：Topoisomerase|Reactive Oxygen Species|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Bomedemstat ditosylate;Chitoheptaose heptahydrochloride;Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CYPMPO;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5 Trending […]

For research use only. We do not sell to patients. SR-3677 CAS No. : 1072959-67-1 Biological Activity：SR-3677 is a potent and selective ROCK-II inhibitor with an IC50 of ~3 nM. Research Area：Cancer Targets：ROCK|Autophagy Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging […]

For research use only. We do not sell to patients. Sodium Salicylate CAS No. : 54-21-7 Biological Activity：Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged […]

For research use only. We do not sell to patients. L-Ascorbic acid-13C CAS No. : 178101-88-7 Biological Activity：L-Ascorbic acid-13C (L-Ascorbate-13C) is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition […]

For research use only. We do not sell to patients. Benzbromarone CAS No. : 3562-84-3 Biological Activity：Benzbromarone is a highly effective and well tolerated non-competitive inhibitor of xanthine oxidase, used as an uricosuric agent, used in the treatment of gout. Research Area：Metabolic Disease Targets：Xanthine Oxidase|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved […]

For research use only. We do not sell to patients. AP-III-a4 CAS No. : 1177827-73-4 Biological Activity：AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic. Research Area：Cancer|Metabolic Disease Targets：Enolase|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer […]