Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. 4′-Hydroxywogonin CAS No. : 57096-02-3 Biological Activity：4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell […]

For research use only. We do not sell to patients. CDK6/PIM1-IN-1 CAS No. : 2677026-14-9 Biological Activity：CDK6/PIM1-IN-1 is a potent and balanced dual CDK6/PIM1 inhibitor with IC50 values of 39 and 88 nM, respectively. CDK6/PIM1-IN-1 inhibits CDK4 (IC50=3.6 nM). CDK6/PIM1-IN-1 significantly inhibits acute myeloid leukemia (AML) cell proliferation, arrest cell cycle at the G1 phase, and promote […]

For research use only. We do not sell to patients. Dihydroartemisinin-d3 CAS No. : 176774-98-4 Biological Activity：Dihydroartemisinin-d3 (Dihydroqinghaosu-d3) is the deuterium labeled Dihydroartemisinin. Dihydroartemisinin is a potent anti-malaria agent. Research Area：Cancer|Infection Targets：Parasite|Autophagy|NF-κB|Apoptosis Related Small Molecules:Physalin A;(+)-Isopulegol;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Icariside F2;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;IKKγ NBD Inhibitory Peptide TFA;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3 Trending products：Recombinant Proteins  |  Bioactive […]

For research use only. We do not sell to patients. Maackiain CAS No. : 19908-48-6 Biological Activity：Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of  21.95 µg/mL. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic […]

For research use only. We do not sell to patients. Isradipine-d3 CAS No. : 1189959-59-8 Biological Activity：Isradipine-d3 (PN 200-110-d3) is the deuterium labeled Isradipine. Isradipine (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as […]

For research use only. We do not sell to patients. Fmoc-Pro-OH-1-13C CAS No. : 2306051-40-9 Biological Activity：Fmoc-Pro-OH-1-13C is a 13C-labeled Sulfabenzamide. Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative ba Research Area：Infection Targets：Autophagy|Bacterial|Antibiotic Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent […]

For research use only. We do not sell to patients. GPX4-IN-3 CAS No. : 2761004-85-5 Biological Activity：GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM. Research Area：Cancer Targets：Ferroptosis|Glutathione Peroxidase Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease […]

For research use only. We do not sell to patients. Daphnetin CAS No. : 486-35-1 Biological Activity：Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, […]

For research use only. We do not sell to patients. ZX-29 CAS No. : 2254805-62-2 Biological Activity：ZX-29 is a potent and selective ALK inhibitor with an IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively. ZX-29 is inactive against EGFR. ZX-29 induces apoptosis by inducing endoplasmic […]

For research use only. We do not sell to patients. Tetramethylcurcumin CAS No. : 52328-97-9 Biological Activity：Tetramethylcurcumin (FLLL31), derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects[2]. Research Area：Cancer|Inflammation/Immunology Targets：STAT|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive […]