Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. GSK-690693 CAS No. : 937174-76-0 Biological Activity：GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent […]

For research use only. We do not sell to patients. Citric acid-13C6 CAS No. : 287389-42-8 Biological Activity：Citric acid-13C6 is the 13C-labeled Citric acid. Citric acid is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a natural preservative and food tartness enhancer. Research Area：Cancer|Infection|Metabolic Disease|Inflammation/Immunology|Cardiovascular Disease Targets：Bacterial|Antibiotic|Endogenous Metabolite|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric […]

For research use only. We do not sell to patients. Topoisomerase II inhibitor 3 CAS No. : 99140-25-7 Biological Activity：Topoisomerase II inhibitor 3 (Compound 6 h ) is a acridone derivatives, as well as a Type II DNA topoisomerase (topo II) inhibitor , as a topo IIα/β inhibitor with the value of IC50 is 0.17 […]

For research use only. We do not sell to patients. Copanlisib-d8 CAS No. : 2168537-35-5 Biological Activity：Copanlisib-d8 (BAY 80-6946-d8) is the deuterium labeled Copanlisib. Copanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, […]

For research use only. We do not sell to patients. ENMD-2076 CAS No. : 934353-76-1 Biological Activity：ENMD-2076 is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively. Research Area：Cancer Targets：FLT3|VEGFR|Src|Aurora Kinase|FGFR|Apoptosis|PDGFR Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical […]

For research use only. We do not sell to patients. Thiamine-13C3 hydrochloride Biological Activity：Thiamine-13C3 (Thiamine chloride-13C3) hydrochloride is the 13C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes. Research Area：Neurological Disease Targets：HBV|Endogenous Metabolite|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;Bomedemstat ditosylate;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy […]

For research use only. We do not sell to patients. Cabozantinib-d6 CAS No. : 1802168-46-2 Biological Activity：Cabozantinib-d6 (XL184-d6) is the deuterium labeled Cabozantinib. Cabozantinib is a potent multiple receptor tyrosine kinases (RTKs) inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively[2][3]. Research Area：Cancer Targets：FLT3|VEGFR|c-Met/HGFR|c-Kit|Apoptosis|TAM […]

For research use only. We do not sell to patients. Fludarabine CAS No. : 21679-14-1 Biological Activity：Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes[2][3][4]. Research Area：Cancer Targets：Nucleoside […]

For research use only. We do not sell to patients. Garcinol CAS No. : 78824-30-3 Biological Activity：Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 µM and 7.39 µM, respectively. Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor […]

For research use only. We do not sell to patients. Deracoxib-d3 CAS No. : 2012598-48-8 Biological Activity：Deracoxib-d3 is the deuterium labeled Deracoxib. Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). Research Area：Inflammation/Immunology Targets：Apoptosis|COX Related Small Molecules:Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;COX-2/5-LOX-IN-3;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D Trending products：Recombinant Proteins  |  […]