Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Sanguinarine chloride CAS No. : 5578-73-4 Biological Activity：Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB. Research Area：Cancer […]

For research use only. We do not sell to patients. Epoxomicin CAS No. : 134381-21-8 Biological Activity：Epoxomicin (BU-4061T) is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can […]

For research use only. We do not sell to patients. Cidofovir CAS No. : 113852-37-2 Biological Activity：Cidofovir (GS 0504) is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, […]

For research use only. We do not sell to patients. Tolcapone CAS No. : 134308-13-7 Biological Activity：Tolcapone (Ro 40-7592) is a selective, orally active and powerful mixed (peripheral and central) COMT inhibitor with an IC50 of 773 nM in the liver. Tolcapone is also a potent inhibitor of α-syn and Aβ42 oligomerization and fibrillogenesis[2]. Tolcapone induces […]

For research use only. We do not sell to patients. Tefinostat CAS No. : 914382-60-8 Biological Activity：Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias. Research Area：Cancer Targets：HDAC|Apoptosis Related Screening […]

For research use only. We do not sell to patients. Nilotinib-d3 CAS No. : 1215678-43-5 Biological Activity：Nilotinib-d3 (AMN107-d3) is the deuterium labeled Nilotinib. Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity[2]. Research Area：Cancer Targets：Autophagy|Bcr-Abl Related Small Molecules:AT9283;Bafetinib;Pivanex;SNIPER(ABL)-039;Flumatinib mesylate;IHMT-TRK-284;SNIPER(ABL)-049;Olverembatinib;GNF-2;CT-721;SNIPER(ABL)-015;GNF-5;BCR-ABL-IN-4;SNIPER(ABL)-033;CHMFL-ABL-039;BCR-ABL-IN-6;c-ABL-IN-2;SNIPER(ABL)-058;ON 146040;HG-7-85-01;CHMFL-ABL/KIT-155;Radotinib-d6;BCR-ABL-IN-1;SIAIS178 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent […]

For research use only. We do not sell to patients. Pentoxifylline-d6 CAS No. : 1185878-98-1 Biological Activity：Pentoxifylline-d6 (BL-191-d6) is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular […]

For research use only. We do not sell to patients. Scriptaid CAS No. : 287383-59-9 Biological Activity：Scriptaid is a potent histone deacetylase (HDAC) inhibitor, used in cancer research. Scriptaid is also a sensitizer to antivirals and has potential for epstein-barr virus (EBV)-associated lymphomas treatment. Research Area：Cancer Targets：Autophagy|Influenza Virus|HDAC|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound […]

For research use only. We do not sell to patients. Flurbiprofen-13C,d3 CAS No. : 2747917-55-9 Biological Activity：Flurbiprofen-13C,d3 is the 13C- and deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. […]

For research use only. We do not sell to patients. SHP2-IN-8 CAS No. : 1801692-60-3 Biological Activity：SHP2-IN-8 is a highly potent, selective, and cellularly active allosteric SHP2 inhibitor with IC50 value of 23 nM and Ki of 22 nM. SHP2-IN-8 is reversible and noncompetitive. SHP2-IN-8 causes a significant thermal shift with the ΔTm of 7.01 […]