Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Lamotrigine hydrate CAS No. : 375347-20-9 Biological Activity：Lamotrigine hydrate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine hydrate selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine hydrate can be used for the research of epilepsy, focal […]

For research use only. We do not sell to patients. PI3Kα-IN-7 CAS No. : 2417098-53-2 Biological Activity：PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor. PI3Kα-IN-7 also inhibits PI3Kβ. PI3Kα-IN-7 decreases cancer cells mitochondrial membrane potential and induces apoptosis. Research Area：Cancer Targets：Apoptosis|PI3K Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Umbralisib hydrochloride;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine […]

For research use only. We do not sell to patients. FL118 CAS No. : 135415-73-5 Biological Activity：FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer[2]. Research Area：Cancer Targets：Survivin|IAP|Apoptosis Related Screening […]

For research use only. We do not sell to patients. EL-102 CAS No. : 1233948-61-2 Biological Activity：EL-102 is a hypoxia-induced factor 1 (Hif1α) inhibitor. EL-102 induces apoptosis, inhibits tubulin polymerisation and shows activities against prostate cancer. EL-102 can be used for the research of cancer. Research Area：Cancer Targets：HIF/HIF Prolyl-Hydroxylase|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis […]

For research use only. We do not sell to patients. Afatinib oxalate CAS No. : 1398312-64-5 Biological Activity：Afatinib (BIBW 2992) oxalate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and […]

For research use only. We do not sell to patients. Delphinidin 3-glucoside chloride CAS No. : 6906-38-3 Biological Activity：Delphinidin 3-glucoside chloride (Delphinidin 3-O-glucoside chloride) is an active anthocyanin found in Hibiscus sabdariffa extract. Delphinidin 3-glucoside chloride induces a pro-apoptotic effect in B cell chronic lymphocytic leukaemia (B CLL). Delphinidin 3-glucoside chloride exerts phytoestrogen activity by […]

For research use only. We do not sell to patients. Amiodarone-d4 hydrochloride CAS No. : 1216715-80-8 Biological Activity：Amiodarone-d4 hydrochloride is the deuterium labeled Amiodarone hydrochloride. Amiodarone hydrochloride, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outwardIhERG tails with an IC50 of ∼45 nM. Amiodarone hydrochloride induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 […]

For research use only. We do not sell to patients. GSK2606414 CAS No. : 1337531-36-8 Biological Activity：GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM. Research Area：Cancer Targets：PERK|Autophagy|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer […]

For research use only. We do not sell to patients. Nafamostat CAS No. : 81525-10-2 Biological Activity：Nafamostat, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis. Nafamostat blocks activation of SARS-CoV-2[2][3][4]. Research Area：Cardiovascular Disease Targets：Ser/Thr Protease|Apoptosis|SARS-CoV Related Small Molecules:Physalin A;Bomedemstat ditosylate;SLN124;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II […]

For research use only. We do not sell to patients. Pectolinarin CAS No. : 28978-02-1 Biological Activity：Pectolinarin possesses anti-inflammatory activity. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2]. Research Area：Inflammation/Immunology Targets：Interleukin […]