Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Tigecycline hydrochloride CAS No. : 197654-04-9 Biological Activity：Tigecycline hydrochloride (GAR-936 hydrochloride) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), […]

For research use only. We do not sell to patients. BTK-IN-9 CAS No. : 2361192-21-2 Biological Activity：BTK-IN-9 is a reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. BTK-IN-9 specifically disturbs mitochondrial membrane potential and increases reactive oxygen species level in Z138 cells. BTK-IN-9 also induces cell apoptosis in Z138 cells. Research Area：Cancer|Inflammation/Immunology […]

For research use only. We do not sell to patients. VTP50469 CAS No. : 2169916-18-9 Biological Activity：VTP50469 is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a Ki of 104 pM. VTP50469 has potently anti-leukemia activity[2]. Research Area：Cancer Targets：Epigenetic Reader Domain|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Histone Modification […]

For research use only. We do not sell to patients. PARP-2-IN-2 Biological Activity：PARP-2-IN-2 (compound 27) is a PARP‑2 inhibitor with an IC50 value of 0.057 µM. PARP-2-IN-2 induces cell cycle arrest and apoptosis of MCF-7 breast cancer cells. PARP-2-IN-2 can be used for the research of cancer. Research Area：Cancer Targets：PARP|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic […]

For research use only. We do not sell to patients. Sabizabulin CAS No. : 1332881-26-1 Biological Activity：VERU-111 (ABI-231) is a potent and orally active α and β tubulin inhibitor, which displays strong antiproliferative activity, with an average IC50 of 5.2 nM against panels of melanoma and prostate cancer cell lines. VERU-111 (ABI-231) suppresses tumor growth […]

For research use only. We do not sell to patients. Metronidazole-d3 CAS No. : 83413-09-6 Biological Activity：Metronidazole-d3 is deuterium labeled Metronidazole. Research Area：Infection Targets：Parasite|Bacterial|Antibiotic|Apoptosis Related Small Molecules:Physalin A;(+)-Isopulegol;Bomedemstat ditosylate;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  […]

For research use only. We do not sell to patients. Chelerythrine chloride CAS No. : 3895-92-9 Biological Activity：Chelerythrine chloride is a potent, cell-permeable inhibitor of protein kinase C, with an IC50 of 660 nM. Chelerythrine chloride inhibits the Bcl-XL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from Bcl-XL. Chelerythrine chloride induces […]

For research use only. We do not sell to patients. Sildenafil CAS No. : 139755-83-2 Biological Activity：Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. Research Area：Cardiovascular Disease|Cancer Targets：Phosphodiesterase (PDE)|Autophagy|Bacterial|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis […]

For research use only. We do not sell to patients. Toyocamycin CAS No. : 606-58-6 Biological Activity：Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of […]

For research use only. We do not sell to patients. MKC-1 CAS No. : 125313-92-0 Biological Activity：MKC-1 (Ro-31-7453) is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin […]