Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. AG490 CAS No. : 133550-30-8 Biological Activity：AG490 (Tyrphostin AG490) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. Research Area：Cancer Targets：EGFR|JAK|Autophagy|STAT Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Stem Cell […]

For research use only. We do not sell to patients. Neobavaisoflavone CAS No. : 41060-15-5 Biological Activity：Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation[2][3][4][5]. Research Area：Cancer Targets：DNA/RNA Synthesis|Apoptosis Related Screening Libraries:Natural […]

For research use only. We do not sell to patients. Samuraciclib hydrochloride hydrate Biological Activity：Samuraciclib (CT7001) hydrochloride hydrate is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib hydrochloride hydrate displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. […]

For research use only. We do not sell to patients. Colchicine-d3 CAS No. : 1217625-62-1 Biological Activity：Colchicine-d3 is the deuterium labeled Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM[2][3]. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)[4]. Research […]

For research use only. We do not sell to patients. Picrasidine Q CAS No. : 101219-61-8 Biological Activity：Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase […]

For research use only. We do not sell to patients. Idarubicin CAS No. : 58957-92-9 Biological Activity：Idarubicin is an orally active and potent anthracycline antileukemic agent. Idarubicin inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin shows induction of DNA damage. Idarubicin inhibits DNA synthesis and of c-myc expression. Idarubicin […]

For research use only. We do not sell to patients. Paris saponin VII CAS No. : 68124-04-9 Biological Activity：Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin […]

For research use only. We do not sell to patients. PF-3758309 dihydrochloride Biological Activity：PF-3758309 (PF-03758309) dihydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 dihydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of […]

For research use only. We do not sell to patients. QTX125 TFA Biological Activity：QTX125 TFA is a potent and highly selective HDAC6 inhibitor. QTX125 TFA exhibits excellent selectivity over other HDACs. QTX125 has antitumor effects. Research Area：Cancer Targets：HDAC|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Histone Modification Research Compound […]

For research use only. We do not sell to patients. Dextran sulfate sodium salt (MW 16000-24000) CAS No. : 9011-18-1 Biological Activity：Dextran sulfate sodium salt (MW 16000-24000) is a is a polymer of anhydroglucose with the molecular weight range of 16000-24000. Dextran sulfate sodium salt inhibits the replication of the human immunodeficiency virus by preventing […]