Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Nafamostat hydrochloride CAS No. : 80251-32-7 Biological Activity：Nafamostat hydrochloride, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat hydrochloride supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis. Nafamostat hydrochloride blocks activation of SARS-CoV-2.[2][3][4]. Research Area：Cardiovascular Disease Targets：Ser/Thr Protease|Apoptosis|SARS-CoV Related Small Molecules:Physalin A;Bomedemstat […]

For research use only. We do not sell to patients. Pemetrexed disodium heptahydrate CAS No. : 357166-29-1 Biological Activity：Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively. Research Area：Cancer […]

For research use only. We do not sell to patients. Amsacrine hydrochloride CAS No. : 54301-15-4 Biological Activity：Amsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Research Area：Cancer Targets：Topoisomerase|Autophagy Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved […]

For research use only. We do not sell to patients. Omeprazole CAS No. : 73590-58-6 Biological Activity：Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative […]

For research use only. We do not sell to patients. L-Asparaginase CAS No. : 9015-68-3 Biological Activity：L-Asparaginase (L-ASNase) is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine, and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with […]

For research use only. We do not sell to patients. SB 202190 CAS No. : 152121-30-7 Biological Activity：SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a […]

For research use only. We do not sell to patients. AAF-CMK CAS No. : 102129-66-8 Biological Activity：AAF-CMK is a TPPII (tripeptidylpeptidase II) inhibitor, shows anti-tumor activity and induces apoptosis. AAF-CMK can be used in leukemia research. Research Area：Cancer Targets：Ser/Thr Protease|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;SLN124;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10 Trending […]

For research use only. We do not sell to patients. VEGFR-2-IN-22 CAS No. : 2447587-73-5 Biological Activity：VEGFR-2-IN-22 (Compound 25) is a dual VEGFR-2 and β-tubulin polymerization inhibitor with an IC50 of 19.82 nM against VEGFR-2. VEGFR-2-IN-22 induces apoptosis. Research Area：Cancer Targets：Microtubule/Tubulin|VEGFR|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;(Z)-FeCP-oxindole;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Tirbanibulin dihydrochloride;BJE6-106;Dinaciclib;VEGFR-2-IN-24;Ecteinascidin 770;MDM2-p53-IN-15;BMS-690514;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Tilavonemab;Mangiferin;Cambinol Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. STAT3-IN-12 Biological Activity：STAT3-IN-12 is a potent STAT3 signal inhibitor that can inhibit IL-6 induced JAK/STAT3 signalling pathway activation. STAT3-IN-12 inhibits cancer cell growth, migration, and induce cell apoptosis as well as cycle arrest. STAT3-IN-12 can be used in cancer-related research, such as hepatocellular carcinoma (HCC) […]

For research use only. We do not sell to patients. Sulforaphene CAS No. : 592-95-0 Biological Activity：Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals[2][3][4]. Research Area：Cancer Targets：EGFR|NF-κB|Apoptosis|ERK Related Screening Libraries:Natural Product […]