Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Prodigiosin hydrochloride CAS No. : 56144-17-3 Biological Activity：Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties[2]. Research […]

For research use only. We do not sell to patients. MIR002 CAS No. : 2217671-64-0 Biological Activity：MIR002 is a potent and orally active DNA polymerase α (POLA1) and HDAC 11 dual inhibitor. MIR002 induces acetylation of p53, activation of p21, G1/S cell cycle arrest, and apoptosis. MIR002 shows significant antitumor activity in vivo. Research Area：Cancer […]

For research use only. We do not sell to patients. Deracoxib CAS No. : 169590-41-4 Biological Activity：Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). IC50 Value: 70 to 150 uM(inhibition of 3 osteosarcoma cell lines) [1] Target: COX in vitro: Concentration of deracoxib required for 50% inhibition of cell viability (IC50) […]

For research use only. We do not sell to patients. GSK1059615 CAS No. : 958852-01-2 Biological Activity：GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Research Area：Cancer Targets：mTOR|Apoptosis|PI3K Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound […]

For research use only. We do not sell to patients. Tubulysin G CAS No. : 799822-08-5 Biological Activity：Tubulysin G is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. […]

For research use only. We do not sell to patients. GLS1 Inhibitor-6 Biological Activity：GLS1 Inhibitor-6 (Compound 24y) is an orally active, potent and selective glutaminase 1 (GLS1) inhibitor (IC50=68 nM), shows 220-fold selectivity for GLS2. GLS1 Inhibitor-6 shows good anti-tumor activity, antitumor cell proliferation activity and induces apoptosis. Research Area：Cancer Targets：Glutaminase|Apoptosis Related Small Molecules:Physalin A;Bomedemstat […]

For research use only. We do not sell to patients. Felodipine-d5 CAS No. : 1242281-38-4 Biological Activity：Felodipine-d5 is deuterium labeled Felodipine. Felodipine, a dihydropyridine, is a potent, vasoselective calcium channel antagonist. Felodipine lowers blood pressure (BP) by selective action on vascular smooth muscle, especially in the resistance vessels. Felodipine, an anti-hypertensive agent, induces autophagy. Felodipine […]

For research use only. We do not sell to patients. PI3K/Akt/mTOR-IN-3 CAS No. : 2457245-94-0 Biological Activity：PI3K/Akt/mTOR-IN-3 (compound 3d) is a potent PI3K/AKT/mTOR inhibitor. PI3K/Akt/mTOR-IN-3 displays the inhibitory activity in MCF-7, HeLa and HepG2 cells, with IC50 values of 0.77, 1.23, and 4.57μM, respectively. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 and HeLa cells at the […]

For research use only. We do not sell to patients. Ciclopirox-d11 sodium Biological Activity：Ciclopirox-d11 (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. […]

For research use only. We do not sell to patients. Caffeic acid phenethyl ester CAS No. : 104594-70-9 Biological Activity：Caffeic acid phenethyl ester is a NF-κB inhibitor. Research Area：Cancer|Inflammation/Immunology Targets：NF-κB|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound […]