Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Anticancer agent 76 CAS No. : 2448091-11-8 Biological Activity：Anticancer agent 76 (Compound CT2-3) is an anticancer agent. Anticancer agent 76 significantly inhibits the proliferation of human NSCLC cells, induces cell cycle arrest, causes ROS generation and induces cell apoptosis. Research Area：Cancer Targets：Topoisomerase|ROS Kinase|Apoptosis|c-Myc Related Small […]

For research use only. We do not sell to patients. HDAC-IN-31 CAS No. : 1916505-13-9 Biological Activity：HDAC-IN-31 is a potent, selective and orally active HDAC inhibitor with IC50s of 84.90, 168.0, 442.7, >10000 nM for HDAC1, HDAC2, HDAC3, HDAC8, respectively. HDAC-IN-31 induces apoptosis and cell cycle arrests at G2/M phase. HDAC-IN-31 shows good antitumor efficacy. […]

For research use only. We do not sell to patients. AP-III-a4 hydrochloride CAS No. : 2070014-95-6 Biological Activity：AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic. Research Area：Cancer|Metabolic Disease Targets：Enolase|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound […]

For research use only. We do not sell to patients. Amiodarone CAS No. : 1951-25-3 Biological Activity：Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM. Research Area：Cardiovascular Disease|Cancer Targets：Autophagy|Potassium Channel Related Small Molecules:Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;IK1 inhibitor PA-6;VU590;Domiphen bromide;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Ketanserin;PE 22-28;Ifenprodil tartrate;Brompheniramine maleate;L-Palmitoylcarnitine-d3 hydrochloride;Phe-Met-Arg-Phe […]

For research use only. We do not sell to patients. Tetrahydrocurcumin CAS No. : 36062-04-1 Biological Activity：Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin. Tetrahydrocurcumin inhibit CYP2C9 and CYP3A4. Research Area：Cancer|Inflammation/Immunology Targets：Autophagy|Endogenous Metabolite|Cytochrome P450 Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound […]

For research use only. We do not sell to patients. Golimumab CAS No. : 476181-74-5 Biological Activity：Golimumab (CNTO-148) is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has […]

For research use only. We do not sell to patients. Prexasertib mesylate CAS No. : 1234015-55-4 Biological Activity：Prexasertib mesylate (LY2606368 mesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of

For research use only. We do not sell to patients. HDAC6-IN-4 CAS No. : 2709103-20-6 Biological Activity：HDAC6-IN-4 (C10) is a potent, orally active and highly selective HDAC6 inhibitor with an IC50 value of 23 nM. HDAC6-IN-4 induces cancer cells apoptosis and shows significant antitumor efficacy, without obvious toxicity. Research Area：Cancer|Inflammation/Immunology Targets：HDAC|Apoptosis Related Small Molecules:Physalin A;Bomedemstat […]

For research use only. We do not sell to patients. (-)-Epigallocatechin CAS No. : 970-74-1 Biological Activity：(-)-Epigallocatechin (Epigallocatechin) is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. Research Area：Cancer Targets：Autophagy|MMP Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. Dacomitinib-d3 Biological Activity：Dacomitinib-d3 (PF-00299804-d3) is the deuterium labeled Dacomitinib. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively. Research Area：Cancer Targets：EGFR|Apoptosis Related Small Molecules:Physalin […]