Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Quinidine CAS No. : 56-54-2 Biological Activity：Quinidine is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinidine can be used for malaria research[2][3][4]. […]

For research use only. We do not sell to patients. VS 8 CAS No. : 2471865-38-8 Biological Activity：VS 8 (Compound VS 8) is a potent, orally active VEGFR-2 inhibitor with significant anti-angiogenic effects. VS 8 induces cancer cell apoptosis and migration. VS 8 is active against CSCs (Cancer stem cells). Research Area：Cancer Targets：Reactive Oxygen Species|VEGFR|Apoptosis […]

For research use only. We do not sell to patients. PD184161 CAS No. : 212631-67-9 Biological Activity：PD184161 is an orally active MEK inhibitor. PD184161 inhibits MEK activity (IC50=10-100 nM) in a time- and concentration-dependent manner. PD184161 inhibits cell proliferation and induces apoptosis. PD184161 produces depressive-like behavior[2]. Research Area：Cancer|Neurological Disease Targets：MEK|Apoptosis Related Screening Libraries:Bioactive Compound Library […]

For research use only. We do not sell to patients. BML-210 CAS No. : 537034-17-6 Biological Activity：BML-210 is a potent HDAC inhibitor. BML-210 can inhibit the HDAC4-VP16-driven reporter signal with an apparent IC50 of ∼5 µM. BML-210 has a specific disruptive effect on the HDAC4:MEF2 interaction. BML-210 causes an increase in the G0/G1 phase. BML-210 induces […]

For research use only. We do not sell to patients. Luxeptinib CAS No. : 1616428-23-9 Biological Activity：Luxeptinib (CG-806) is an orally active, reversible, first-in-class, non-covalent and potent pan-FLT3/pan-BTK inhibitor. Luxeptinib induces cell cycle arrest, apoptosis or autophagy in acute myeloid leukemia cells[2][3][4]. Research Area：Cancer Targets：FLT3|Btk|Apoptosis Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound […]

For research use only. We do not sell to patients. Daunorubicin hydrochloride CAS No. : 23541-50-6 Biological Activity：Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also […]

For research use only. We do not sell to patients. Dipyridamole CAS No. : 58-32-2 Biological Activity：Dipyridamole is an orally active phosphodiesterase (PDE) inhibitor. Dipyridamole also is an antiplatelet agent used in secondary prophylaxis against stroke. Dipyridamole can induce cancer cell-specific apoptosis[2][3]. Research Area：Cardiovascular Disease|Cancer Targets：Phosphodiesterase (PDE)|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug […]

For research use only. We do not sell to patients. Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA CAS No. : 199807-33-5 Biological Activity：Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) can be used for the research of acute myeloid leukemia. Research Area：Cancer Targets：Integrin|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library;Cyclic Peptide Library; Related Small […]

For research use only. We do not sell to patients. Oxypeucedanin CAS No. : 737-52-0 Biological Activity：Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial […]

For research use only. We do not sell to patients. Triptonide CAS No. : 38647-11-9 Biological Activity：Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects[2]. Research Area：Cancer|Inflammation/Immunology Targets：Wnt|Autophagy|β-catenin|Apoptosis Related Screening […]