Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Dihydroartemisinin CAS No. : 71939-50-9 Biological Activity：Dihydroartemisinin is a potent anti-malaria agent. Research Area：Cancer|Infection Targets：Parasite|Autophagy|NF-κB|Apoptosis Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Immunology/Inflammation Compound Library; NF-κB Signaling […]

For research use only. We do not sell to patients. Alisertib CAS No. : 1028486-01-2 Biological Activity：Alisertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor (IC50=1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib (MLN 8237) induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 […]

For research use only. We do not sell to patients. Valinomycin CAS No. : 2001-95-8 Biological Activity：Valinomycin (NSC 122023), a cyclic depsipeptide antibiotic, act as a potassium selective ionophore. Valinomycin (NSC 122023) inhibits lymphocyte proliferation by its effects on the cell membrane, and induces apoptosis in CHO cells. Valinomycin induces activation of PINK1 leading to […]

For research use only. We do not sell to patients. Pentoxifylline-d5 CAS No. : 1185995-18-9 Biological Activity：Pentoxifylline-d5 (BL-191-d5) is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular […]

For research use only. We do not sell to patients. Baohuoside I CAS No. : 113558-15-9 Biological Activity：Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity. Research Area：Cancer|Inflammation/Immunology|Endocrinology Targets：CXCR|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;GPCR/G […]

For research use only. We do not sell to patients. VEGFR-2-IN-14 Biological Activity：VEGFR-2-IN-14 (Compound 5) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-14 arrests the HepG2 cell growth at the Pre-G1 phase and induces apoptosis. Research Area：Cancer Targets：VEGFR|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;(Z)-FeCP-oxindole;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;VEGFR-2-IN-24;Ecteinascidin 770;MDM2-p53-IN-15;BMS-690514;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  […]

For research use only. We do not sell to patients. Rabeprazole-d4 sodium Biological Activity：Rabeprazole-d4 sodium (LY307640-d4 sodium) is the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an […]

For research use only. We do not sell to patients. Oxaprozin CAS No. : 21256-18-8 Biological Activity：Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces […]

For research use only. We do not sell to patients. NSC-87877 CAS No. : 56990-57-9 Biological Activity：NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26)[2]. Research Area：Others Targets：SHP2|Phosphatase|Apoptosis Related Screening […]

For research use only. We do not sell to patients. 9-Methoxycamptothecin CAS No. : 39026-92-1 Biological Activity：9-Methoxycamptothecin (MCPT), isolated from Camptotheca acuminata, has antitumor activities through topoisomerase inhibition. 9-Methoxycamptothecin (MCPT) induces strong G2/M arrest and apoptosis in cancer[2]. Research Area：Cancer Targets：Topoisomerase|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound […]