Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. Daunorubicin citrate CAS No. : 1884557-85-0 Biological Activity：Daunorubicin (Daunomycin) citrate is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin citrate inhibits DNA and RNA synthesis. Daunorubicin citrate is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin citrate is also […]

For research use only. We do not sell to patients. Everolimus-d4 CAS No. : 1338452-54-2 Biological Activity：Everolimus-d4 (RAD001-d4) is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell […]

For research use only. We do not sell to patients. Wogonin CAS No. : 632-85-9 Biological Activity：Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt, and exhibits anti-inflammatory and anti-tumor effects. Research Area：Cancer|Inflammation/Immunology Targets：Wnt|Autophagy|CDK|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound […]

For research use only. We do not sell to patients. SB 202190 hydrochloride CAS No. : 350228-36-3 Biological Activity：SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 […]

For research use only. We do not sell to patients. Chemerin-9 (149-157) CAS No. : 676367-27-4 Biological Activity：Chemerin-9 (149-157) is a potent agonist of chemokine-like receptor 1 (CMKLR1) . Chemerin-9 (149-157) has anti-inflammatory activity. Chemerin-9 (149-157) stimulates phosphorylation of Akt and ERK as well as ROS production. Chemerin-9 (149-157) ameliorates Aβ1-42-induced memory impairmen. Chemerin-9 (149-157) […]

For research use only. We do not sell to patients. Calcimycin hemicalcium salt CAS No. : 59450-89-4 Biological Activity：Calcimycin hemicalcium salt (A-23187 hemicalcium salt) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemicalcium salt induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium salt inhibits the growth […]

For research use only. We do not sell to patients. Imipramine-d4 hydrochloride CAS No. : 61361-33-9 Biological Activity：Imipramine-d4 hydrochloride is the deuterium labeled Imipramine hydrochloride. Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. Imipramine hydrochloride is a Fascin1 inhibitor with antitumor activities. Imipramine hydrochloride also inhibits serotonin transporter with an IC50 value of […]

For research use only. We do not sell to patients. MARK4 inhibitor 1 CAS No. : 2271081-58-2 Biological Activity：MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. Research Area：Cancer Targets：Apoptosis|AMPK Related Screening Libraries:Bioactive Compound Library […]

For research use only. We do not sell to patients. Glyburide-d3 CAS No. : 1219803-02-7 Biological Activity：Glyburide-d3 (Glyburide-d3) is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 […]

For research use only. We do not sell to patients. Forodesine hydrochloride CAS No. : 284490-13-7 Biological Activity：Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent […]