Tag: Inducer|Inhibitor

For research use only. We do not sell to patients. EI1 CAS No. : 1418308-27-6 Biological Activity：EI1 (KB-145943) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively. Research Area：Cancer Targets：Histone Methyltransferase|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound […]

For research use only. We do not sell to patients. Filanesib CAS No. : 885060-09-3 Biological Activity：Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity. Research Area：Cancer Targets：Kinesin|Apoptosis Related Screening […]

For research use only. We do not sell to patients. Galanthamine-O-methyl-d3 CAS No. : 1279031-09-2 Biological Activity：Galanthamine-O-methyl-d3 is the deuterium labeled Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM. Research Area：Neurological Disease Targets：Cholinesterase (ChE)|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Piperilate Trending […]

For research use only. We do not sell to patients. Torin 1 CAS No. : 1222998-36-8 Biological Activity：Torin 1 is a potent inhibitor of mTOR with an IC50 of 3 nM. Torin 1 inhibits both mTORC1/2 complexes with IC50 values between 2 and 10 nM. Torin 1 is an effective inducer of autophagy. Research Area：Cancer […]

For research use only. We do not sell to patients. Nitazoxanide CAS No. : 55981-09-4 Biological Activity：Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 […]

For research use only. We do not sell to patients. GSK778 CAS No. : 2451862-42-1 Biological Activity：GSK778 (iBET-BD1) is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. GSK778 phenocopies the effects […]

For research use only. We do not sell to patients. Dihydromyricetin CAS No. : 27200-12-0 Biological Activity：Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor […]

For research use only. We do not sell to patients. PARP1-IN-12 Biological Activity：PARP1-IN-12 is a potent PARP1 inhibitor with an IC50 of 2.99 nM. PARP1-IN-12 exhibits antiproliferative activity, can induce cell apoptosis and cause cycle arrest at G2/M phase. PARP1-IN-12 also can induce DNA double strand breaks (DSBs) in BRCA-deficient cells. Research Area：Cancer Targets：PARP|Apoptosis Related […]

For research use only. We do not sell to patients. Lasalocid sodium CAS No. : 25999-20-6 Biological Activity：Lasalocid sodium (Lasalocid-A sodium) treatment led to an increase in cell wall thickness, whilst the quantity and sugar composition of the cell wall remained unchanged in BY-2 cells. Lasalocid sodium (Lasalocid-A sodium) treatment enhances enzymatic saccharification efficiency in […]

For research use only. We do not sell to patients. NAMPT degrader-1 Biological Activity：NAMPT degrader-1 (Compound A3) is an nicotinamide phosphoribosyltransferase (NAMPT) degrader with an IC50 of 0.023 μM. NAMPT degrader-1 significantly induces the degradation of NAMPT through the autophagy-lysosomal pathway and shows excellent cellular antitumor potency. Research Area：Cancer Targets：Autophagy|NAMPT Related Small Molecules:Teglarinad chloride;CB 300919;GNE-617;NAMPT […]