Tag: Inducer|Activator

For research use only. We do not sell to patients. AlbA-DCA CAS No. : 2413716-79-5 Biological Activity：AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A (AlbA) to a dichloroacetate acid (DCA) subunit. AlbA-DCA can induce a marked increase in intracellular ROS and alleviate the accumulation of lactic acid in tumor microenvironment (TME), and […]

For research use only. We do not sell to patients. Trabectedin CAS No. : 114899-77-3 Biological Activity：Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS […]

For research use only. We do not sell to patients. Dehydrotrametenolic acid CAS No. : 6879-05-6 Biological Activity：Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects. Research Area：Cancer|Inflammation/Immunology Targets：Caspase|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II […]

For research use only. We do not sell to patients. Antitumor agent-72 Biological Activity：Antitumor agent-72 (compound 6w) is a potent anticancer agent. Antitumor agent-72 has anticancer activity and induces apoptosis through activation of caspase-3 and cleavage of PARP. Antitumor agent-72 can be used for cancer research. Research Area：Cancer Targets：PARP|Caspase|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin […]

For research use only. We do not sell to patients. NS1643 CAS No. : 448895-37-2 Biological Activity：NS1643 is a partial agonist of human ether-a-go-go-related gene (hERG) K(+) channels with an EC50 of 10.5 μM. NS1643 has distinct effects on erg2 (Kv11.2) currents by reducing channel inactivation especially at high concentrations. NS1643 increases the repolarization reserve […]

For research use only. We do not sell to patients. Ezetimibe-d4 diacetate CAS No. : 1217861-13-6 Biological Activity：Ezetimibe-d4 diacetate is the deuterium labeled Ezetimibe. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator[2]. Research Area：Cardiovascular Disease|Cancer Targets：Autophagy|Keap1-Nrf2 Related Small Molecules:Mangiferin;Antioxidant agent-5;Curcumin;Antroquinonol;Resveratrol;NXPZ-2;Eriodictyol;ML334;S-Allylmercaptocysteine;NK-252;Ginsenoside Rh3;4-Hydroxyphenylacetic […]

For research use only. We do not sell to patients. Apoptotic agent-2 CAS No. : 2482310-18-7 Biological Activity：Apoptotic agent-2 (compound 14b) induces apoptosis by down-regulation of Bcl-2 and up-regulation of Bax and caspase-3. Apoptotic agent-2 exhibits anti-proliferative activities and can be used for cancer research. Research Area：Cancer Targets：Bcl-2 Family|Caspase|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin […]

For research use only. We do not sell to patients. JS-K CAS No. : 205432-12-8 Biological Activity：JS-K is a NO donor that reacts with glutathione to generate NO at physiological pH. JS-K inhibits proliferation, induces apoptosis, and disrupts the cell cycle of Jurkat T acute lymphoblastic leukemia cells[2]. Research Area：Cancer Targets：NO Synthase|Apoptosis Related Small Molecules:Carboxy-PTIO […]

For research use only. We do not sell to patients. Diazoxide CAS No. : 364-98-7 Biological Activity：Diazoxide (Sch-6783) is an ATP-sensitive potassium channel activator, has the potential for hyperinsulinism treatment. Research Area：Cardiovascular Disease|Cancer Targets：Autophagy|Potassium Channel Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;FDA-Approved […]

For research use only. We do not sell to patients. Trigonelline CAS No. : 535-83-1 Biological Activity：Trigonelline, an alkaloid with potential antidiabetic activity, is present in Trigonella foenum-graecum L. Trigonelline is an efficient Nrf2 inhibitor capable of blocking Nrf2-dependent proteasome activity and thereby apoptosis protection in pancreatic cancer cells. Research Area：Cancer|Metabolic Disease Targets：Ferroptosis|Endogenous Metabolite|Apoptosis Related […]