Tag: Inducer|Activator

For research use only. We do not sell to patients. 740 Y-P TFA Biological Activity：740 Y-P TFA is a potent and cell-permeable PI3K activator. 740 Y-P TFA readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone. Research Area：Cancer Targets：Autophagy|PI3K Related Small Molecules:Umbralisib […]

For research use only. We do not sell to patients. Anticancer agent 58 Biological Activity：Anticancer agent 58 (compound 16) has inhibitory activity against kinds of cancer cell lines, especially in A549 and T24 with IC50s of 0.6 μM and 0.7 μM, respectively. Anticancer agent 58 induces apoptosis by activating caspase 3/8/9 activity, and induces an […]

For research use only. We do not sell to patients. Decursin CAS No. : 5928-25-6 Biological Activity：Decursin ((+)-Decursin) is a potent anti-tumor agent. Decursin also is a cytotoxic agent and a potent protein kinase C activator. Decursin induces apoptosis and cell cycle arrest at G1 phase. Decursin decreases the expression of CDK2, CDK4, CDK6, cyclin […]

For research use only. We do not sell to patients. ML291 CAS No. : 1523437-16-2 Biological Activity：ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic […]

For research use only. We do not sell to patients. 7,8-Dihydroneopterin CAS No. : 1218-98-0 Biological Activity：7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases. Research Area：Inflammation/Immunology|Neurological Disease Targets：NO Synthase|Endogenous Metabolite|Apoptosis Related Small Molecules:Carboxy-PTIO potassium;D-α-Hydroxyglutaric […]

For research use only. We do not sell to patients. Oleic acid-d2 CAS No. : 5711-29-5 Biological Activity：Oleic acid-d2 (9-cis-Octadecenoic acid-d2) is the deuterium labeled Oleic acid. Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator[2]. Research Area：Cancer|Metabolic Disease Targets：Na+/K+ ATPase|Endogenous Metabolite|Apoptosis Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin […]

For research use only. We do not sell to patients. Cearoin CAS No. : 52811-37-7 Biological Activity：Cearoin increases autophagy and apoptosis through the production of ROS and the activation of ERK. Research Area：Cancer Targets：Autophagy|Reactive Oxygen Species|Apoptosis|ERK Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Physalin A;Bomedemstat ditosylate;Chitoheptaose heptahydrochloride;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;N-Acetyl-D-cysteine;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;CYPMPO;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9 Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Forskolin CAS No. : 66575-29-9 Biological Activity：Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various […]

For research use only. We do not sell to patients. 5-Aminolevulinic acid-15N hydrochloride CAS No. : 116571-80-3 Biological Activity：5-Aminolevulinic acid-15N (5-ALA-15N) hydrochloride is the 15N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles. Research Area：Metabolic Disease|Cancer Targets：Autophagy|Mitophagy|Endogenous Metabolite|Apoptosis Related Small […]

For research use only. We do not sell to patients. Trabectedin D3 Biological Activity：Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the […]