Tag: Inducer

For research use only. We do not sell to patients. Lenalidomide CAS No. : 191732-72-6 Biological Activity：Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, […]

For research use only. We do not sell to patients. Antiproliferative agent-7 CAS No. : 2497687-47-3 Biological Activity：Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 […]

For research use only. We do not sell to patients. Corynoxine CAS No. : 6877-32-3 Biological Activity：Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway. Research Area：Cancer|Neurological Disease Targets：Autophagy Related Screening Libraries:Natural Product Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. Silibinin CAS No. : 22888-70-6 Biological Activity：Silibinin (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration. Research Area：Cancer Targets：Autophagy|Reactive Oxygen Species Related Screening Libraries:Natural Product Library Plus;Drug Repurposing […]

For research use only. We do not sell to patients. Glycochenodeoxycholic acid CAS No. : 640-79-9 Biological Activity：Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[2]. Research Area：Cancer Targets：Endogenous […]

For research use only. We do not sell to patients. ICy-OH Biological Activity：ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm，λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway. Research Area：Cancer Targets：Pyroptosis Related Small Molecules:Ac-FEID-CMK […]

For research use only. We do not sell to patients. L-threo-PPMP CAS No. : 207278-87-3 Biological Activity：L-threo-PPMP is a GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) inhibitor. L-threo-PPMP inhibits glycosphingolipid biosynthesis and induces apoptosis. L-threo-PPMP has anti-cancer activity. Research Area：Cancer Targets：Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium Trending products：Recombinant […]

For research use only. We do not sell to patients. Anticancer agent 43 CAS No. : 2470015-35-9 Biological Activity：Anticancer Agent 43 is a potent anticancer agent. Anticancer Agent 43 induces apoptosis by caspase 3, PARP1, and Bax dependent mechanisms. Anticancer Agent 43 induces DNA damage. Research Area：Cancer Targets：PARP|Bcl-2 Family|Caspase|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin […]

For research use only. We do not sell to patients. AK-778-XXMU CAS No. : 1227045-76-2 Biological Activity：AK-778-XXMU is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth. Research […]

For research use only. We do not sell to patients. Pomalidomide-d3 CAS No. : 2093128-28-8 Biological Activity：Pomalidomide-d3 (CC-4047-d3) is the deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors[2]. Research Area：Cancer Targets：Ligands for E3 Ligase|Apoptosis|Molecular Glues Related […]