Tag: Antagonist|Inhibitor

For research use only. We do not sell to patients. Rimonabant CAS No. : 168273-06-1 Biological Activity：Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Research Area：Infection|Metabolic Disease|Cancer Targets：Bacterial|Cannabinoid Receptor Related Small Molecules:Sandramycin;LLO […]

For research use only. We do not sell to patients. PD98059 CAS No. : 167869-21-8 Biological Activity：PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by […]

For research use only. We do not sell to patients. Methicillin sodium hydrate CAS No. : 7246-14-2 Biological Activity：Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used […]

For research use only. We do not sell to patients. Ranitidine bismuth citrate CAS No. : 128345-62-0 Biological Activity：Ranitidine bismuth citrate is an orally active Histamine H2-receptor antagonist with an IC50 of 3.3 μM. Ranitidine bismuth citrate has high selectivity for SARS-CoV-2-infected cells. Ranitidine bismuth citrate is a commonly used agent anti-Helicobacter pylori infection with […]

For research use only. We do not sell to patients. MCH-1 antagonist 1 CAS No. : 1039825-68-7 Biological Activity：MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist with a Ki of 2.6 nM. MCH-1 antagonist 1 also inhibits CYP3A4 with an IC50 of 10 μM. Research Area：Metabolic Disease|Endocrinology Targets：MCHR1 (GPR24)|Cytochrome P450 Related Small […]

For research use only. We do not sell to patients. Angiotensin (1-7) CAS No. : 51833-78-4 Biological Activity：Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts […]

For research use only. We do not sell to patients. Astemizole CAS No. : 68844-77-9 Biological Activity：Astemizole (R 43512), a second-generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an […]

For research use only. We do not sell to patients. ACH-806 CAS No. : 870142-71-5 Biological Activity：ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. Research Area：Infection Targets：HCV|HCV Protease Related Small Molecules:HCV-IN-30;NS5A-IN-1;HCV-IN-38;Sennidin A;HCV-IN-31;Radalbuvir;Grazoprevir potassium salt;FGI-106 tetrahydrochloride;BMS-986144;Oenothein B;Triton X-45(n=4);Mecarbinate;Artemisinin-d3;TTP-8307;HCV-IN-34;Miravirsen;Ciluprevir;Faldaprevir-d6;Isoeuphorbetin;MK-0608;Setrobuvir Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  […]

For research use only. We do not sell to patients. Cinanserin hydrochloride CAS No. : 54-84-2 Biological Activity：Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of […]

For research use only. We do not sell to patients. Fenspiride hydrochloride CAS No. : 5053-08-7 Biological Activity：Fenspiride, an orally active non-steroidal antiinflammatory agent, is an antagonist of H1-histamine receptor. Fenspiride inhibites phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4) and phosphodiesterase 5 (PDE5) activities with -log IC50 values of 3.44, 4.16 and approximately 3.8, respectively. Fenspiride […]