Tag: Antagonist|Inhibitor

For research use only. We do not sell to patients. Clemizole CAS No. : 442-52-4 Biological Activity：Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole is an inhibitor of TRPC5 channel. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication […]

For research use only. We do not sell to patients. CCR5 antagonist 1 CAS No. : 716354-86-8 Biological Activity：CCR5 antagonist 1 is a CCR5 antagonist which can inhibit HIV replication extracted from WO 2004054974 A2. Research Area：Infection|Endocrinology Targets：HIV|CCR Related Small Molecules:HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;LMD-009;FC131;Peritassine A;PF-04634817 succinate;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine;Islatravir Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Thiethylperazine dimaleate CAS No. : 1179-69-7 Biological Activity：Thiethylperazine dimaleate, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine dimaleate is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine dimaleate has anti-emetic, antipsychotic and antimicrobial […]

For research use only. We do not sell to patients. Rimonabant Hydrochloride CAS No. : 158681-13-1 Biological Activity：Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Research Area：Cancer|Infection|Metabolic Disease […]

For research use only. We do not sell to patients. Trimipramine-d3 maleate CAS No. : 1185245-93-5 Biological Activity：Trimipramine-d3 maleate is the deuterium labeled Trimipramine maleate. Trimipramine maleate is a 5-HT receptor antagonist, with pKis of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively[2]. Research Area：Neurological Disease Targets：5-HT Receptor|Bacterial Related Small Molecules:F 13714;Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium […]

For research use only. We do not sell to patients. Bis(7)-tacrine dihydrochloride CAS No. : 224445-12-9 Biological Activity：Bis(7)-tacrine dihydrochloride is a dimeric AChE inhibitor derived from tacrine. Bis(7)-tacrine dihydrochloride prevents glutamate-induced neuronal apoptosis by blocking NMDA receptors. Bis(7)-tacrine dihydrochloride is a potent GABAAreceptor antagonist. Bis(7)-tacrine dihydrochloride has the potential for the research of Alzheimer’s disease […]

For research use only. We do not sell to patients. Diphylline CAS No. : 479-18-5 Biological Activity：Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator drug and has the potential for chronic bronchitis and emphysema[2]. Research Area：Inflammation/Immunology|Cardiovascular Disease Targets：Phosphodiesterase (PDE)|Adenosine Receptor […]

For research use only. We do not sell to patients. 6-Diazo-5-oxo-L-nor-Leucine CAS No. : 157-03-9 Biological Activity：6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial […]

For research use only. We do not sell to patients. Oxybutynin CAS No. : 5633-20-5 Biological Activity：Oxybutynin is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM. Research Area：Neurological Disease Targets：mAChR|Potassium Channel Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound […]

For research use only. We do not sell to patients. Drotaverine-d10 hydrochloride Biological Activity：Drotaverine-d10 hydrochloride is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3′,5′-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without […]