Tag: Antagonist

For research use only. We do not sell to patients. SB-334867 free base CAS No. : 792173-99-0 Biological Activity：SB-334867 free base (SB334867A free base) is an excellent, selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 reduces […]

For research use only. We do not sell to patients. Granisetron Hydrochloride CAS No. : 107007-99-8 Biological Activity：Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library […]

For research use only. We do not sell to patients. Levobunolol CAS No. : 47141-42-4 Biological Activity：Levobunolol (l-Bunolol) is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol can be used for glaucoma and superior oblique myokymia (SOM) research[2][3]. Research Area：Others Targets：Adrenergic Receptor Related […]

For research use only. We do not sell to patients. NGB 2904 hydrochloride CAS No. : 189061-11-8 Biological Activity：NGB 2904 hydrochloride is a potent, selective, orally active and brain-penetrated antagonist of dopamine D3 receptor, with a Ki of 1.4 nM. NGB 2904 hydrochloride shows selectivity for D3 over D2, 5-HT2, α1, D4, D1 and D5 […]

For research use only. We do not sell to patients. Ondansetron-d5 CAS No. : 1219798-86-3 Biological Activity：Ondansetron-d5 (GR 38032-d5) is the deuterium labeled Ondansetron. Ondansetron (GR 38032; SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy. Research Area：Neurological Disease Targets：5-HT Receptor Related Small Molecules:F […]

For research use only. We do not sell to patients. Tetrahydroalstonine CAS No. : 6474-90-4 Biological Activity：Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist[2]. Research Area：Endocrinology|Neurological Disease Targets：Adrenergic Receptor Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus; Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline […]

For research use only. We do not sell to patients. Cangrelor CAS No. : 163706-06-7 Biological Activity：Cangrelor (AR-C69931MX), an adenosine triphosphate analogue, is an intravenous, reversible and selective platelet P2Y12 antagonist, with prompt and potent antiplatelet effects. Cangrelor directly blocks adenosine diphosphate (ADP)-induced activation and aggregation of platelets. Cangrelor is also a nonspecific GPR17 antagonist[2]. […]

For research use only. We do not sell to patients. HX531 CAS No. : 188844-34-0 Biological Activity：HX531 is a potent RXR antagonist with an IC50 of 18 nM. It has been shown to reduce triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice on a high fat diet[2]. Research Area：Metabolic Disease […]

For research use only. We do not sell to patients. LPA2 antagonist 2 CAS No. : 36840-10-5 Biological Activity：LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. LPA2 antagonist 2 is >480-fold more selective than LPA3 (IC50 of 13.85 μM). Research Area：Cancer […]

For research use only. We do not sell to patients. MoTP CAS No. : 57055-82-0 Biological Activity：MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer. Research Area：Cancer Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid […]