Tag: Antagonist

For research use only. We do not sell to patients. ORM-15341 CAS No. : 1297537-33-7 Biological Activity：ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. IC50 value: 38 […]

For research use only. We do not sell to patients. Orphenadrine citrate CAS No. : 4682-36-4 Biological Activity：Orphenadrine citrate is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a Ki of 6.0 μM. Orphenadrine citrate relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine citrate […]

For research use only. We do not sell to patients. Neurokinin antagonist 1 CAS No. : 214487-45-3 Biological Activity：Neurokinin antagonist 1 is a Neurokinin antagonist extracted from patent WO1998045262A1. Research Area：Inflammation/Immunology|Endocrinology Targets：Neurokinin Receptor Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);Talnetant hydrochloride;Pavinetant;MEN11467;(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P;Vapreotide acetate;Rolapitant;Eprazinone dihydrochloride;Orvepitant maleate;Netupitant metabolite Monohydroxy Netupitant;SB-222200;Senktide;GR 87389;Hemokinin 1, human;Neurokinin A TFA;Imnopitant dihydrochloride;[Glp6] Substance P (6-11);[Lys5,MeLeu9,Nle10]-NKA(4-10) […]

For research use only. We do not sell to patients. CCR3 antagonist 1 CAS No. : 879399-82-3 Biological Activity：CCR3 antagonist 1 is a potent antagonist of CCR3, used for the research of immunologic and inflammatory diseases. Research Area：Inflammation/Immunology|Endocrinology Targets：CCR Related Small Molecules:LMD-009;PF-04634817 succinate;Vercirnon;CKLF1-C27;Bindarit;CCR6 antagonist 1;CCR6 inhibitor 1;CCR4-351 hydrochloride;BI 639667;ML604086;CCR4 antagonist 3-1;AZD2423;AZD2098;AZD-1678;R243;RS102895 hydrochloride;Vicriviroc maleate;BMS-639623;AZD-4818;INCB 3284 dimesylate;Maceneolignan […]

For research use only. We do not sell to patients. TTA-A2 CAS No. : 953778-63-7 Biological Activity：TTA-A2 is a potent, selective and orally active t-type voltage gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and […]

For research use only. We do not sell to patients. Amisulpride CAS No. : 71675-85-9 Biological Activity：Amisulpride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively. Research Area：Cancer|Neurological Disease Targets：Dopamine Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive […]

For research use only. We do not sell to patients. BAY-218 CAS No. : 2162982-11-6 Biological Activity：BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 μM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with […]

For research use only. We do not sell to patients. DNQX disodium salt CAS No. : 1312992-24-7 Biological Activity：DNQX (FG 9041) disodium salt, a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively). Research Area：Cancer Targets：iGluR Related Small Molecules:CIQ;Quinolinic […]

For research use only. We do not sell to patients. S 38093 CAS No. : 862896-30-8 Biological Activity：S 38093 is a brain-penetrant, orally active antagonist of H3 receptor, with Kis of 8.8, 1.44 and 1.2 µM for rat, mouse and human H3 receptors, respectively. Research Area：Neurological Disease|Endocrinology Targets：Histamine Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G […]

For research use only. We do not sell to patients. Pentapeptide-3 CAS No. : 135679-88-8 Biological Activity：Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1, it can be extracted from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging […]