Tag: Antagonist

For research use only. We do not sell to patients. Androgen receptor antagonist 2 CAS No. : 1272719-00-2 Biological Activity：Androgen receptor antagonist 2 (example 12) is an androgen receptor antagonist. Androgen receptor antagonist 2 can be used for prostate cancer and male hair loss research. Research Area：Cancer|Metabolic Disease Targets：Androgen Receptor Related Small Molecules:VPC-14449;AC-262536;GTx-007;Linuron-d6;MI-136;VPC-13789;RD162;ARD-2585;PF-998425;GSK-2881078;PROTAC AR Degrader-4;RU […]

For research use only. We do not sell to patients. Sparsentan-d5 CAS No. : 1801597-09-0 Biological Activity：Sparsentan-d5 is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. Research Area：Cardiovascular Disease|Endocrinology Targets：Angiotensin Receptor|Endothelin Receptor Related Small Molecules:BQ-788;[Asn18] Endothelin-1, human;Saralasin;Endothelin-3, human, […]

For research use only. We do not sell to patients. RO 4938581 CAS No. : 883093-10-5 Biological Activity：RO 4938581 is a potent and selective GABAA α5 inverse agonist, with a Ki of 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, 174, 185, 80 nM, respectively); RO 4938581 is […]

For research use only. We do not sell to patients. Lusaperidone CAS No. : 214548-46-6 Biological Activity：Lusaperidone (R107474) is an α2 adrenergic receptor antagonist with Kis of 0.13 and 0.15 nM for α2A and α2C, respectively. Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Endocrinology Compound Library;Neurotransmitter […]

For research use only. We do not sell to patients. Losartan Carboxylic Acid CAS No. : 124750-92-1 Biological Activity：Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic […]

For research use only. We do not sell to patients. 3-Hydroxy agomelatine-d3-1 Biological Activity：3-Hydroxy agomelatine-d3-1 is the deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is a metabolite of Agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM. Research Area：Neurological Disease Targets：5-HT Receptor Related Small Molecules:F […]

For research use only. We do not sell to patients. V-9302 hydrochloride CAS No. : 2416138-42-4 Biological Activity：V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells. Research Area：Cancer Targets：Others […]

For research use only. We do not sell to patients. 1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone CAS No. : 120693-52-9 Biological Activity：Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC50=48.2 μM). Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is a quinolone alkaloid from Evodia rutaecarpa. Research Area：Endocrinology|Cardiovascular Disease Targets：Angiotensin Receptor Related Small Molecules:Saralasin;A81988;EMD 66684;TD-0212;Angiotensin I/II (1-6) (TFA);YS-49;TRV055;TRV056;H-Val-Pro-Pro-OH TFA;Tranilast sodium;Angiotensin amide;L162389;L-159282;CGP48369;Elisartan;Pratosartan;TRV-120027 TFA;SL910102 Trending products：Recombinant Proteins  |  Bioactive […]

For research use only. We do not sell to patients. PROTAC ERRα ligand 1 CAS No. : 1264754-13-3 Biological Activity：PROTAC ERRα ligand 1 is an estrogen-related receptor α (ERRα) antagonist with IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively. Research Area：Cancer Targets：Estrogen Receptor/ERR Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:DS20362725;LSD1/ER-IN-1;Giredestrant;Avobenzone;Estriol-d3;Chrysin;ERRγ […]

For research use only. We do not sell to patients. 5-BDBD CAS No. : 768404-03-1 Biological Activity：5-BDBD, a potent and selective P2X4 receptor antagonist, inhibits rP2X4R-mediated currents, with an IC50 of 0.75 μM. 5-BDBD completely blocks the basal and acute hyperalgesia induced by nitroglycerin (NTG)[2]. Research Area：Neurological Disease Targets：P2X Receptor Related Screening Libraries:Bioactive Compound Library […]