Tag: Antagonist

For research use only. We do not sell to patients. Nonapeptide-1 CAS No. : 158563-45-2 Biological Activity：Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, […]

For research use only. We do not sell to patients. ZK168281 CAS No. : 186371-96-0 Biological Activity：ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure VDR antagonist with a Kd value of 0.1 nM. ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor. Research Area：Metabolic Disease Targets：VD/VDR Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. Ziconotide TFA Biological Activity：Ziconotide TFA (SNX-111 TFA), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide TFA reduces synaptic transmission, and can be used for chronic pain research. Research Area：Inflammation/Immunology|Neurological Disease Targets：Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM 1003;Glaucine;Efonidipine hydrochloride […]

For research use only. We do not sell to patients. K-(D-1-Nal)-FwLL-NH2 TFA Biological Activity：K-(D-1-Nal)-FwLL-NH2 TFA is a high affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). K-(D-1-Nal)-FwLL-NH2 blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways. Targets：GHSR Related Small Molecules:Relamorelin acetate;(αR,8aS)-GSK1614343;Capromorelin Tartrate;BMS-604992 dihydrochloride;Macimorelin;TM-N1324;L-692585;Anamorelin hydrochloride;Obestatin(rat) […]

For research use only. We do not sell to patients. Atosiban acetate CAS No. : 914453-95-5 Biological Activity：Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research. Research Area：Cancer|Endocrinology Targets：Oxytocin Receptor|Vasopressin Receptor Related […]

For research use only. We do not sell to patients. BAY-u 9773 CAS No. : 154978-38-8 Biological Activity：BAY-u 9773 is a non-selective antagonist of the CysLT receptors (cysteinyl leukotrienes receptors) with about the same IC50 for CysLT1 and CysLT2. BAY-u9773 is used for the inhibition of LT responses. Research Area：Inflammation/Immunology Targets：Leukotriene Receptor Related Small Molecules:Pranlukast-d4;Verlukast-d6;Ablukast;CP-96486;MK-886;BIIL-260 […]

For research use only. We do not sell to patients. Etoxadrol CAS No. : 28189-85-7 Biological Activity：Etoxadrol (CL-1848C) is a potent N-methyl-D-aspartic acid (NMDA) antagonist with high affinity. Etoxadrol can be used for anaesthetic research. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant […]

For research use only. We do not sell to patients. INCB 3284 dimesylate CAS No. : 887401-93-6 Biological Activity：INCB 3284 dimesylate is a potent, selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2, with an IC50 of 3.7 nM. INCB 3284 dimesylate can be used in the research of acute […]

For research use only. We do not sell to patients. Vofopitant CAS No. : 168266-90-8 Biological Activity：Vofopitant is potent tachykinin NK1 receptor antagonist, with pKis of 10.6, 9.5, and 9.8 for human, rat and ferret NK1 receptor, respectively. Research Area：Neurological Disease|Endocrinology Targets：Neurokinin Receptor Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);Talnetant hydrochloride;Pavinetant;MEN11467;(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P;Vapreotide acetate;Rolapitant;Eprazinone dihydrochloride;Orvepitant maleate;Netupitant metabolite Monohydroxy […]

For research use only. We do not sell to patients. CGP55845 hydrochloride CAS No. : 149184-22-5 Biological Activity：CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC50 of 6 nM. CGP55845 hydrochloride can be used for neurological research[2]. Research Area：Neurological Disease Targets：GABA Receptor Related Small Molecules:SKF89976A hydrochloride;mGAT-IN-1;Alpidem;FG8119;Valerenic acid;Picrotoxinin;Miltirone;Etifoxine-13C,d3;Adipiplon;Gabazine;Broflanilide;Fluxametamide;ONO-8590580;γ-Aminobutyric acid-d6;Ginsenoside Rc;Fipronil;p-Hydroxybenzaldehyde-13C;Lesogaberan hydrochloride;FG 7142;Isoguvacine […]