Tag: Antagonist

For research use only. We do not sell to patients. BIM-23056 CAS No. : 150155-61-6 Biological Activity：BIM 23056, a linear octapeptide, is a potent sst3 and sst5 somatostatin receptor antagonist with Ki values of 10.8, 5.7, respectively. Research Area：Neurological Disease Targets：Somatostatin Receptor Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library; Related Small Molecules:Cortistatin 29;L-803087 TFA;Pasireotide;SSTR5 antagonist […]

For research use only. We do not sell to patients. Palosuran CAS No. : 540769-28-6 Biological Activity：Palosuran (ACT-058362) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran can improves pancreatic and renal function in diabetic rats[2]. Research […]

For research use only. We do not sell to patients. UFP-803 TFA Biological Activity：UFP-803 TFA is a potent urotensin-II receptor (UT) ligand. UFP-803 TFA has lower residual agonist activity, so it may be an important tool for the investigations on the role played by the UT system in physiology and pathology. Research Area：Cardiovascular Disease Targets：Urotensin […]

For research use only. We do not sell to patients. Valsartan-d9 CAS No. : 1089736-73-1 Biological Activity：Valsartan-d9 (CGP 48933-d9) is deuterium labeled valsartan. Valsartan is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research. Research Area：Cardiovascular Disease|Endocrinology Targets：Angiotensin Receptor Related Small Molecules:Saralasin;A81988;EMD 66684;TD-0212;Angiotensin I/II (1-6) (TFA);YS-49;TRV055;TRV056;H-Val-Pro-Pro-OH TFA;Tranilast […]

For research use only. We do not sell to patients. L-798106 CAS No. : 244101-02-8 Biological Activity：L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has  micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM, respectively. Research Area：Cancer Targets：Prostaglandin […]

For research use only. We do not sell to patients. LY2444296 CAS No. : 1346133-11-6 Biological Activity：LY2444296 is an orally bioavailable, high-affinity and selective short-acting kappa opioid receptor (KOPR) antagonist, with a Ki value of ∼1 nM. LY2444296 exhibits anti-anxiety like effects[2]. Research Area：Neurological Disease Targets：Opioid Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound […]

For research use only. We do not sell to patients. NDT 9513727 CAS No. : 439571-48-9 Biological Activity：NDT 9513727 is a potent, selective, orally active and competitive inverse agonist of the human C5aR (C5a receptor), with an IC50 of 11.6 nM. NDT 9513727 can be used for the research of human inflammatory diseases. Research Area：Inflammation/Immunology […]

For research use only. We do not sell to patients. GluR6 antagonist-1 CAS No. : 323176-64-3 Biological Activity：GluR6 antagonist-1 is a benzothiophene derivative, acting as a GluR6 antagonist. GluR6 antagonist-1 can be used for researching acute and chronic neurological disorders. Research Area：Neurological Disease Targets：iGluR Related Small Molecules:CIQ;Quinolinic acid-d3;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;ZL006;PYD-106;NMDA-IN-2;JAMI1001A;(S)-Willardiine;Fanapanel;(S)-AMPA;L-Glutamic acid-15N,d5;PDZ1 Domain inhibitor peptide TFA;Ifenprodil tartrate;Rislenemdaz;Coluracetam;Flupirtine-d4 […]

For research use only. We do not sell to patients. BV6 CAS No. : 1001600-56-1 Biological Activity：BV6 is an antagonist of cIAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. Research Area：Cancer Targets：IAP Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Anti-Prostate Cancer Compound Library; Related Small Molecules:Xevinapant;XIAP degrader-1;MX69;APG-1387;SBP-0636457;GDC-0152;Birinapant;TD1092;SM-164;CUDC-427;SM-1295;LCL161;AZD5582;MV1;XIAP/cIAP1 antagonist-1;FL118;Polygalacin D;SM-433 hydrochloride;LBW242;UC-112;ASTX660;SM-433;Embelin […]

For research use only. We do not sell to patients. Zaurategrast ethyl ester CAS No. : 455264-30-9 Biological Activity：Zaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders[2]. Research Area：Inflammation/Immunology Targets：Integrin Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive […]