Tag: Antagonist

For research use only. We do not sell to patients. Tolazoline CAS No. : 59-98-3 Biological Activity：Tolazoline(Imidaline) is a non-selective competitive α-adrenergic receptor antagonist. Research Area：Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine hemitartrate;ADRA1D receptor antagonist 1;Solabegron Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  […]

For research use only. We do not sell to patients. Ifetroban CAS No. : 143443-90-7 Biological Activity：Ifetroban (BMS-180291) is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban can be used for myocardial ischemia, hypertension, stroke, thrombosis, […]

For research use only. We do not sell to patients. Fasitibant chloride CAS No. : 1157852-02-2 Biological Activity：Fasitibant chloride (MEN16132 free base) is a potent and selective nonpeptide bradykinin B2 receptor (B2R) antagonist. Fasitibant chloride reduces joint pain and diminishes joint oedema in Carrageenan-induced arthritis rat model[2][3]. Research Area：Neurological Disease|Cardiovascular Disease Targets：Bradykinin Receptor Related Small […]

For research use only. We do not sell to patients. AS-35 CAS No. : 108427-72-1 Biological Activity：AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum with IC50 values of 8 nM, 4 nM and 3 nM, respectively, and has antiallergic activities. Research Area：Inflammation/Immunology Targets：Leukotriene […]

For research use only. We do not sell to patients. Levobunolol hydrochloride CAS No. : 27912-14-7 Biological Activity：Levobunolol (l-Bunolol) hydrochloride is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol hydrochloride is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol hydrochloride can be used for glaucoma and superior oblique myokymia (SOM) research[2][3]. Research […]

For research use only. We do not sell to patients. NOD1/2 antagonist-1 CAS No. : 2704623-69-6 Biological Activity：NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding oligomerization domain-like receptor 1/2) dual antagonist, with IC50 values of 1.13 (NOD1) and 0.77 μM (NOD2), respectively. NOD1/2 antagonist-1 has a acceptable T1/2 (67.6 min). NOD1/2 antagonist-1 (compound 36b) […]

For research use only. We do not sell to patients. Cetirizine dihydrochloride CAS No. : 83881-52-1 Biological Activity：Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[2][3]. Research Area：Inflammation/Immunology|Endocrinology Targets：Histamine Receptor […]

For research use only. We do not sell to patients. SB 218795 CAS No. : 174635-53-1 Biological Activity：SB 218795 is a potent and selective non-peptide NK3 receptor antagonist, with a Ki 13 nM for hNK3. SB 218795 shows about 90-fold and 7000-fold selectivity for hNK3 over hNK2 and hNK1, respectively. SB 218795 can inhibit NK3 […]

For research use only. We do not sell to patients. ICI 192605 CAS No. : 117621-64-4 Biological Activity：ICI 192605 is a potent TXA2R (thromboxane A2 receptor) antagonist as cell signaling prostaglandin. ICI 192605 blocks contraction of isolated guinea pig trachea induced by U-46619. Research Area：Endocrinology Targets：Prostaglandin Receptor Related Small Molecules:Omidenepag isopropyl;DG-041;8-Isoprostaglandin E2;BAY-6672;trans-Isoferulic acid;GSK-269984A;KMN-80;SC 51089;p-Hydroxycinnamic acid;Pexopiprant;Dinoprost;Sulprostone;Prostaglandin […]

For research use only. We do not sell to patients. NBD-14189 CAS No. : 2234273-72-2 Biological Activity：NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV-1HXB2 pseudovirus. NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC50