Tag: Antagonist

For research use only. We do not sell to patients. Terazosin hydrochloride CAS No. : 63074-08-8 Biological Activity：Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and […]

For research use only. We do not sell to patients. Aminopterin CAS No. : 54-62-6 Biological Activity：Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer […]

For research use only. We do not sell to patients. A1AR antagonist 1 Biological Activity：A1AR antagonist 1 (compound 18g) is a potent A1 adenosine receptor (AR) antagonist with Kis of 2.08, 6.91, and 31.2 nM for hA1, hA2A and hA2B, respectively. Research Area：Neurological Disease Targets：Adenosine Receptor Related Small Molecules:MRS 1523;APNEA;MIPS521;Derenofylline;FSCPX;Theobromine-d3;Inosine-13C;Norisoboldine;N-0861 racemate;Xanthine amine congener dihydrochloride;LUF6096;A1/A3 AR antagonist […]

For research use only. We do not sell to patients. Fenmetozole Tosylate CAS No. : 83474-08-2 Biological Activity：Fenmetozole Tosylate is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor, and acts as an antidepressant drug. Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine […]

For research use only. We do not sell to patients. D4R antagonis-2 Biological Activity：D4R antagonist-2 is a potent and selective D4R antagonist with an IC50 of 6.52 µM. D4R antagonist-2 displays very favorable in vitro PK parameters and has good brain penetration. D4R antagonist-2 has the potential for the research of Parkinson’s disease. Research Area：Neurological […]

For research use only. We do not sell to patients. BMS-639623 CAS No. : 675122-44-8 Biological Activity：BMS-639623 is a potent and orally activeCCR3 antagonist with an IC50 of 0.3 nM. BMS-639623 picomolar inhibition potency against eosinophil chemotaxis (IC50=38 pM). BMS-639623 can be used for the research of asthma. Research Area：Inflammation/Immunology Targets：CCR Related Small Molecules:LMD-009;PF-04634817 succinate;Vercirnon;CKLF1-C27;Bindarit;CCR6 […]

For research use only. We do not sell to patients. Mozavaptan-d6 CAS No. : 2750534-83-7 Biological Activity：Mozavaptan-d6 (OPC-31260-d6) is the deuterium labeled Mozavaptan. Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM. Mozavaptan shows ~85-fold selectivity for V2 receptor over […]

For research use only. We do not sell to patients. Cyclobenzaprine-d6 hydrochloride CAS No. : 2748492-38-6 Biological Activity：Cyclobenzaprine-d6 (hydrochloride) is deuterium labeled Cyclobenzaprine (hydrochloride). Research Area：Neurological Disease Targets：5-HT Receptor Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Renzapride;LY 344864 racemate;Harmine hydrochloride;Valerenic acid;Arotinolol;Melitracen-d6 hydrochloride;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Tetrahydro-β-carboline;CP-809101;Volinanserin-d4 hydrochloride;Masupirdine free base;BRL-15572 dihydrochloride;LY393558;Brexpiprazole S-oxide Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  […]

For research use only. We do not sell to patients. Antalarmin hydrochloride CAS No. : 220953-69-5 Biological Activity：Antalarmin (hydrochloride) is a non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory […]

For research use only. We do not sell to patients. 2-Hydroxysaclofen CAS No. : 117354-64-0 Biological Activity：2-Hydroxysaclofen is a potent γ-amino-butyric-acid-B (GABAB) receptor antagonist. 2-Hydroxysaclofen can abolish nicotine-induced hypolocomotor effects and increases the antinociceptive effects. 2-Hydroxysaclofen can stimulate luteinizing hormone (LH) secretion in female rats[2][3]. Research Area：Endocrinology|Neurological Disease Targets：GABA Receptor Related Small Molecules:SKF89976A hydrochloride;mGAT-IN-1;Alpidem;FG8119;Valerenic acid;Picrotoxinin;Miltirone;Etifoxine-13C,d3;Adipiplon;Gabazine;Broflanilide;Fluxametamide;ONO-8590580;γ-Aminobutyric […]