Tag: Antagonist

For research use only. We do not sell to patients. Transcrocetin CAS No. : 27876-94-4 Biological Activity：Transcrocetin (trans-Crocetin), extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. Transcrocetin (trans-Crocetin) is capable of crossing the blood-brain barrier and reach the central nervous system (CNS)[2]. Research Area：Cancer Targets：Endogenous Metabolite|iGluR Related Screening […]

For research use only. We do not sell to patients. SNT-207858 free base CAS No. : 1104662-66-9 Biological Activity：SNT207858 free base is a selective, blood brain barrier penetrating, potent and orally active melanocortin-4 (MC-4) receptor antagonist. SNT207858 free base has an IC50 of 22 nM (binding) and 11 nM (function) on the MC-4 receptor. Research […]

For research use only. We do not sell to patients. BMS-195614 CAS No. : 182135-66-6 Biological Activity：BMS-195614 (BMS 614) is a neutral RARα-selective antagonist with a Ki of 2.5 nM. Research Area：Cancer Targets：RAR/RXR Related Small Molecules:AGN 193109-d7;Retinoic acid;AC-261066;Magnolol;ER 50891;(+)-Talarozole;Trifarotene;β-Apo-13-carotenone;Bigelovin;CD2665;BMS453;9-cis-Retinoic acid;AGN-195183;Fenretinide;Liarozole dihydrochloride;LE135;Tamibarotene;UVI 3003;PROTAC RAR Degrader-1;BMS641;Tarenflurbil Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  […]

For research use only. We do not sell to patients. Montelukast sodium CAS No. : 151767-02-1 Biological Activity：Montelukast sodium (MK0476) is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (CysLT1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in […]

For research use only. We do not sell to patients. Methoxy-PEPy CAS No. : 524924-76-3 Biological Activity：Methoxy-PEPy is a potent and highly selective mGlu5 receptor antagonist with IC50 of 1 nM. IC50 value: 1 nM [1] Target: mGlu5R inhibitor Administration of [3H]methoxy-PEPy (50 microCi/kg i.v.) to mGlu5 receptor-deficient mice revealed binding at background levels in […]

For research use only. We do not sell to patients. Nor-benzetimide CAS No. : 19315-71-0 Biological Activity：Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity[2]. Research Area：Neurological Disease Targets：mAChR Related Small Molecules:VU0357017 hydrochloride;TBPB;Imidafenacin;Sabcomeline;MK-6884;Brompheniramine-d6 maleate;Navafenterol saccharinate;DREADD agonist 21;Cyclobuxine D;Brompheniramine maleate;Dexetimide;Anisodamine hydrobromide;Anisotropine bromide;PD 102807;Nebracetam hydrochloride;Muscarine-d9 iodide;Mazaticol;VU0455691;Arborine;Oxitropium Bromide;Propiverine hydrochloride;VU0152099;MHP 133;YM-58790;Elucaine;Rispenzepine;Phenglutarimid;Rapacuronium bromide;Ambutonium bromide;Temiverine […]

For research use only. We do not sell to patients. Fosaprepitant CAS No. : 172673-20-0 Biological Activity：Fosaprepitant (L-785298) is a prodrug of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV). Research Area：Neurological Disease|Endocrinology Targets：Neurokinin Receptor Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);Talnetant hydrochloride;Pavinetant;MEN11467;(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P;Vapreotide acetate;Rolapitant;Eprazinone […]

For research use only. We do not sell to patients. UniPR129 CAS No. : 1639159-47-9 Biological Activity：UniPR129 is a potent Eph/ephrin antagonist. UniPR129 has the potential for the research of cancer disease. Research Area：Cancer Targets：Ephrin Receptor Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Angiogenesis-Related Compound Library; Related Small Molecules:LDN-211904 […]

For research use only. We do not sell to patients. YM-298198 hydrochloride CAS No. : 1216398-09-2 Biological Activity：YM-298198 hydrochloride is a high-affinity, selective, orally active, and non-competitive antagonist of metabotropic glutamate receptor type 1 (mGluR1). YM-298198 hydrochloride can be used for the research of neurological disorders. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator […]

For research use only. We do not sell to patients. RC-3095 CAS No. : 138147-78-1 Biological Activity：RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist. RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice[2]. Research Area：Inflammation/Immunology Targets：Bombesin Receptor Related Small Molecules:PD176252;Bombesin;BA 1;BIM-26226;ML-18;Kuwanon H;MK-5046;Litorin;Ranatensin;Kuwanon G;PD 168368 Trending products：Recombinant Proteins  |  Bioactive Screening […]