Tag: Antagonist

For research use only. We do not sell to patients. Thioperamide maleate CAS No. : 148440-81-7 Biological Activity：Thioperamide maleate (MR-12842 maleate) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a Ki of 4.3 nM for inhibition of [3H]histamine release. Thioperamide maleate inhibits [3H]histamine synthesis with a Ki of 31 nM. […]

For research use only. We do not sell to patients. Silodosin-d4 CAS No. : 1426173-86-5 Biological Activity：Silodosin-d4 (KAD 3213-d4) is the deuterium labeled Silodosin. Silodosin (KAD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR […]

For research use only. We do not sell to patients. SR33805 CAS No. : 121345-64-0 Biological Activity：SR33805 is a potent Ca2+ channel antagonist, with EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively. SR33805 blocks L-type but not T-type Ca2+ channels. SR33805 can be used for the research of acute or […]

For research use only. We do not sell to patients. Abarelix Acetate Biological Activity：Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research. Research Area：Cancer|Endocrinology Targets：GnRH Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound […]

For research use only. We do not sell to patients. SB-408124 Hydrochloride CAS No. : 1431697-90-3 Biological Activity：SB-408124 Hydrochloride is a selective non-peptide orexin receptor 1 (OX1) receptor antagonist with Kis of 57 nM and 27 nM in whole cell and membrane, respectively. SB-408124 Hydrochloride exhibits 50-fold selectivity over OX2 receptor. Research Area：Neurological Disease|Endocrinology Targets：Orexin […]

For research use only. We do not sell to patients. Bosentan (hydrate) CAS No. : 157212-55-0 Biological Activity：Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Research Area：Cardiovascular Disease|Endocrinology Targets：Endothelin Receptor Related Screening Libraries:Drug Repurposing […]

For research use only. We do not sell to patients. Carteolol hydrochloride CAS No. : 51781-21-6 Biological Activity：Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma. Research Area：Cardiovascular Disease|Endocrinology Targets：Adrenergic Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling […]

For research use only. We do not sell to patients. Bometolol Hydrochloride CAS No. : 65023-16-7 Biological Activity：Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease. Research Area：Cardiovascular Disease|Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine hemitartrate;ADRA1D receptor antagonist 1;Solabegron […]

For research use only. We do not sell to patients. MAP4 CAS No. : 157381-42-5 Biological Activity：MAP4 is a selective group III mGluR antagonist in some electrophysiological systems. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 hydrochloride;Cinnabarinic acid;LY379268;AZD 9272;mGluR2 antagonist 1;ABP688;FTIDC;MPPG;L-AP3;VU6001966;VU0155041 sodium;VU 0364439;trans-ACPD;AZD-8529 mesylate;VU 0357121;PHCCC;HexylHIBO;VU0650786 Trending products：Recombinant Proteins  |  Bioactive Screening […]

For research use only. We do not sell to patients. A 438079 hydrochloride CAS No. : 899431-18-6 Biological Activity：A 438079 (hydrochloride) is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9. Research Area：Neurological Disease Targets：P2X Receptor Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neurotransmitter Receptor Compound Library;Neuroprotective Compound Library;Human Metabolite Library; Related Small Molecules:Gefapixant citrate;JNJ-47965567;AF-353;Oxatomide;AZ10606120 […]