Tag: Antagonist

For research use only. We do not sell to patients. Haloperidol-13C6 Biological Activity：Haloperidol-13C6 is the 13C6 labeled Haloperidol. Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic. Research Area：Neurological Disease Targets：Dopamine Receptor Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Bromopride-d3;Nuciferine;Glaucine;SB-277011 dihydrochloride;MIF-1 TFA;Sulpiride;(Rac)-Razpipadon;Clebopride malate;WAY-100635;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Itopride-d6 hydrochloride;ONC206;Brexpiprazole S-oxide;cis-(Z)-Flupentixol dihydrochloride;D4R antagonist-1;U91356 Trending products：Recombinant Proteins  |  Bioactive Screening […]

For research use only. We do not sell to patients. Almokalant CAS No. : 123955-10-2 Biological Activity：Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current. Research Area：Cardiovascular Disease Targets：Potassium Channel Related Small Molecules:Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;IK1 inhibitor […]

For research use only. We do not sell to patients. Piboserod hydrochloride CAS No. : 178273-87-5 Biological Activity：Piboserod (SB 207266) Hcl is a selective 5-HT(4) receptor antagonist. IC50 value: Target: 5-HT4 antagonist in vitro: Piboserod did not modify the basal contractions but concentration-dependently antagonized the ability of 5-HT to enhance bladder strip contractions to EFS. […]

For research use only. We do not sell to patients. p-Hydroxybenzaldehyde CAS No. : 123-08-0 Biological Activity：p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. Research Area：Neurological Disease Targets：GABA Receptor|Endogenous Metabolite Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive […]

For research use only. We do not sell to patients. PF 04531083 CAS No. : 1079400-07-9 Biological Activity：PF 04531083 is a selective NaV1.8 blocker, and used for the research of neuropathic/inflammatory pain. Research Area：Neurological Disease Targets：Sodium Channel Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Clinical Compound […]

For research use only. We do not sell to patients. Triprolidine hydrochloride monohydrate CAS No. : 6138-79-0 Biological Activity：Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats[2][3]. Research […]

For research use only. We do not sell to patients. NF023 hexasodium CAS No. : 104869-31-0 Biological Activity：NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses respectively[2][3][4]. Research Area：Neurological Disease Targets：P2X […]

For research use only. We do not sell to patients. AHR antagonist 2 CAS No. : 2338747-54-7 Biological Activity：AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1, with IC50s of 0.885 and 2.03 nM for human and mouse AhR. Research Area：Cancer Targets：Aryl Hydrocarbon Receptor Related Screening […]

For research use only. We do not sell to patients. (D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P CAS No. : 115760-58-2 Biological Activity：(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P is a selective NK1 receptor antagonist. Research Area：Neurological Disease Targets：Neurokinin Receptor Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);Talnetant hydrochloride;Pavinetant;MEN11467;(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P;Vapreotide acetate;Rolapitant;Eprazinone dihydrochloride;Orvepitant maleate;Netupitant metabolite Monohydroxy Netupitant;SB-222200;Senktide;GR 87389;Hemokinin 1, human;Neurokinin A TFA;Imnopitant dihydrochloride;[Glp6] Substance P (6-11);[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA;[Pro9]-Substance P;Befetupitant;Hemokinin 1 […]

For research use only. We do not sell to patients. Conantokin G CAS No. : 93438-65-4 Biological Activity：Conantokin G, a 17-amino-acid peptide, is a potent, selective and competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. Conantokin G inhibits NMDA-evoked currents in murine cortical neurons with an IC50 of 480 nM. Conantokin G has neuroprotective properties[2]. Research Area：Neurological […]