Tag: Antagonist

For research use only. We do not sell to patients. Fexofenadine CAS No. : 83799-24-0 Biological Activity：Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research[2][3]. Research Area：Inflammation/Immunology Targets：Histamine Receptor Related Small Molecules:Tripelennamine;Brompheniramine-d6 maleate;Samelisant;Chlorphenoxamine;H3 receptor-MO-1;Diphenhydramine;ABT-239;Ketotifen fumarate;Ranitidine;Cetirizine;Diphenylpyraline hydrochloride;Loratadine-d5;Phenyltoloxamine;Ritanserin;BMY-25271;FRG8701;Mecamylamine hydrochloride;Cimetidine sulfoxide;Brompheniramine maleate;Tecastemizole;Famotidine-13C,d3;Bromazine-d6 hydrochloride Trending […]

For research use only. We do not sell to patients. Procyclidine CAS No. : 77-37-2 Biological Activity：Procyclidine (Tricyclamol; (±)-Procyclidine), an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine can be used in studies of Parkinson’s disease and related psychiatric disorders such as Soman-induced epilepsy[2]. Research […]

For research use only. We do not sell to patients. R243 CAS No. : 688352-84-3 Biological Activity：R243 is a potent and selective CCR8 antagonist. R243 inhibits CCL1/CCR8 interaction and inhibits CCR8 signaling and chemotaxis. R243 has antinociceptive and anti-inflammatory effects[2]. Research Area：Inflammation/Immunology Targets：CCR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Small Molecule […]

For research use only. We do not sell to patients. Valsartan ethyl ester-d9 Biological Activity：Valsartan ethyl ester-d9 is the deuterium labeled Valsartan Ethyl Ester. Valsartan Ethyl Ester is an impurity of Valsartan. Valsartan is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure. Research Area：Cardiovascular Disease Targets：Angiotensin Receptor Related […]

For research use only. We do not sell to patients. Darodipine CAS No. : 72803-02-2 Biological Activity：Darodipine (PY 108-068, PY-108068) is a potent calcium channel antagonist. Research Area：Neurological Disease|Cardiovascular Disease Targets：Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM 1003;Glaucine;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;MRS 1523;Nilvadipine;Lercanidipine;CP-060;Anipamil-d25 hydrochloride;ISX-9;ω-Conotoxin MVIIC;Catharanthine;Thapsigargin;Tetrandrine;Ginsenoside Rd;Manidipine dihydrochloride;ω-Agatoxin IVA;AE0047 Hydrochloride;PDE1-IN-4 Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. MA-2029 CAS No. : 287206-61-5 Biological Activity：MA-2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4.9 nM). MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility. […]

For research use only. We do not sell to patients. tcY-NH2 CAS No. : 327177-34-4 Biological Activity：tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) is a potent selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology[2][6]. Research Area：Metabolic Disease|Inflammation/Immunology Targets：Protease Activated Receptor (PAR) Related Small Molecules:ENMD-1068 […]

For research use only. We do not sell to patients. Irdabisant CAS No. : 1005402-19-6 Biological Activity：Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with Ki values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low […]

For research use only. We do not sell to patients. PD 90780 CAS No. : 77422-99-2 Biological Activity：PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and […]

For research use only. We do not sell to patients. RS102895 hydrochloride CAS No. : 1173022-16-6 Biological Activity：RS102895 hydrochloride is a potent CCR2 antagonist, with an IC50 of 360 nM, and shows no effect on CCR1. Research Area：Neurological Disease|Endocrinology Targets：CCR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Small Molecule Immuno-Oncology Compound Library;Endocrinology […]