Tag: Antagonist

For research use only. We do not sell to patients. Bimekizumab CAS No. : 1418205-77-2 Biological Activity：Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises IL-17A and IL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation. Research Area：Inflammation/Immunology Targets：Interleukin […]

For research use only. We do not sell to patients. Spiperone CAS No. : 749-02-0 Biological Activity：Spiperone is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone is a widely used pharmacological tool. Spiperone has the potential for the research of neurology diseases. Research Area：Neurological Disease Targets：Dopamine Receptor|5-HT Receptor Related Screening Libraries:Drug Repurposing […]

For research use only. We do not sell to patients. AZD-1678 CAS No. : 942137-41-9 Biological Activity：AZD-1678 is a potent CCR4 receptor antagonist, with a pIC50 of 8.6. Research Area：Others Targets：CCR Related Small Molecules:LMD-009;PF-04634817 succinate;Vercirnon;CKLF1-C27;Bindarit;CCR6 antagonist 1;CCR6 inhibitor 1;CCR4-351 hydrochloride;BI 639667;ML604086;CCR4 antagonist 3-1;AZD2423;AZD2098;R243;RS102895 hydrochloride;Vicriviroc maleate;BMS-639623;AZD-4818;INCB 3284 dimesylate;Maceneolignan H;CKLF1-C27 TFA;CCR3 antagonist 1;C-021;INCB3344;RPT193 Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. OSW-1 CAS No. : 145075-81-6 Biological Activity：OSW-1, isolated from Ornithogalum caudatum, is a specific antagonist of osterol-binding protein (OSBP) and OSBP-related protein 4 (ORP4) with GI50s in the nanomolar range in human cancer lines. Research Area：Cancer Targets：Others Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library […]

For research use only. We do not sell to patients. Barnidipine-d5 hydrochloride Biological Activity：Barnidipine-d5 (Mepirodipine-d5) hydrochloride is the deuterium labeled Barnidipine hydrochloride. Barnidipine hydrochloride (Mepirodipine hydrochloride) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. Barnidipine hydrochloride (Mepirodipine hydrochloride) is an antihypertensive […]

For research use only. We do not sell to patients. (S)-Terazosin CAS No. : 109351-33-9 Biological Activity：(S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinity α-adrenoceptor antagonist with Ki values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. (S)-Terazosin also has high-affinity for α2a, α2B […]

For research use only. We do not sell to patients. Androgen receptor antagonist 5 CAS No. : 2586195-28-8 Biological Activity：Androgen receptor antagonist 5 (compound 42f) is a potent androgen receptor (AR) antagonist with an IC50 value of 6.17 μM. Androgen receptor antagonist 5 can effectively impair AR nuclear translocation, reducing the levels of nuclear AR, […]

For research use only. We do not sell to patients. L-745870 hydrochloride CAS No. : 1173023-36-3 Biological Activity：L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, […]

For research use only. We do not sell to patients. H4R antagonist 1 CAS No. : 1429375-54-1 Biological Activity：H4R antagonist 1 is a potent and highly selective histamine H4 receptor (H4R) antagonist with an IC50 of 27 nM. H4R antagonist 1 does not show any noticeable binding affinity to other subtypes of histamine receptors, H1R, […]

For research use only. We do not sell to patients. SL910102 CAS No. : 144756-71-8 Biological Activity：SL910102 is a nonpeptide angiotensin AT1 receptor antagonist. Research Area：Cardiovascular Disease|Endocrinology Targets：Angiotensin Receptor Related Small Molecules:Saralasin;A81988;EMD 66684;TD-0212;Angiotensin I/II (1-6) (TFA);YS-49;TRV055;TRV056;H-Val-Pro-Pro-OH TFA;Tranilast sodium;Angiotensin amide;L162389;L-159282;CGP48369;Elisartan;Pratosartan;TRV-120027 TFA Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  […]